N-(叔丁氧基羰基)-3-溴苯胺合成路线 (共 6 条)
参考文献
Abbott Laboratories
Patent: US5432194 A1, 1995 ;
反应条件
in dichloromethane T=20°C; 18 h;
参考文献
GALDERMA RESEARCH and DEVELOPMENT, S.N.C.
Patent: WO2006/18326 A1, 2006 ;
Location in patent: Page/Page column 16; 17 ;
WO 2006/018326 A1
参考文献
Abbott Laboratories
Patent: US5484786 A1, 1996 ;
反应条件
potassium acetate in dichloromethane; ethyl acetate; N,N-dimethyl-formamide
参考文献
Abbott Laboratories
Patent: US6921763 B2, 2005 ;
反应条件
molecular sieve; boron trifluoride diethyl etherate in dichloromethane Ambient temperature;
参考文献
Evans, Emily F.; Lewis, Norman J.; Kapfer, Isabelle; Macdonald, Gregor; Taylor, Richard J. K.
Synthetic Communications, 1997 , vol. 27, # 11 p. 1819 - 1825
反应条件
1: (3-bromo-phenyl)-carbamic acid t-butyl ester With sodium hydride in DMF (N,N-dimethyl-formamide)
2: methyl iodide in DMF (N,N-dimethyl-formamide)
T=20°C; 5 h;
参考文献
GALDERMA RESEARCH and DEVELOPMENT, S.N.C.
Patent: WO2004/113331 A1, 2004 ;
Location in patent: Page 91 ;