三环[3.3.1.13,7]癸-2-亚基乙酸合成路线 （共 5 条）
反应条件
sulfuric acid in dichloromethane T=20°C; 3 h; Yield given;
参考文献
Panteleon, Vassiliki; Kostakis, Ioannis K.; Marakos, Panagiotis; Pouli, Nicole; Andreadou, Ioanna
Bioorganic and Medicinal Chemistry Letters, 2008 , vol. 18, # 21 p. 5781 - 5784
反应条件
1: ethyl acetate With lithium diisopropyl amide 2: adamantane monoketone (adamantanone) 3: With sulfuric acid
参考文献
Schreiner, Erwin P.; Wolff, Barbara; Winiski, Anthony P.; Billich, Andreas
Bioorganic and Medicinal Chemistry Letters, 2003 , vol. 13, # 24 p. 4313 - 4316
反应条件
1: With sodium hydride Horner-Emmons olefination; 2: With sodium hydroxide
参考文献
Schreiner, Erwin P.; Wolff, Barbara; Winiski, Anthony P.; Billich, Andreas
Bioorganic and Medicinal Chemistry Letters, 2003 , vol. 13, # 24 p. 4313 - 4316
反应条件
2: 96percent sulfuric acid / CH2Cl2 / 3 h / 20 °C View Scheme
参考文献
Masters, Andrew P.; Sorensen, Ted S.; Tran, Phu Mahn
Canadian Journal of Chemistry, 1987 , vol. 65, p. 1499 - 1502
反应条件
(i) Zn, toluene, benzene, (ii) aq. NaOH, EtOH, (iii) H2SO4, benzene; Multistep reaction;
参考文献
Scharp,J. et al.
Recueil des Travaux Chimiques des Pays-Bas, 1970 , vol. 89, p. 18 - 22
