3-甲基-4-氧代戊酸甲酯合成路线 （共 17 条）
反应条件
tetrabutylammomium bromide in N,N-dimethyl-formamide
T=25°C; electrochemical reduction;
参考文献
Ohno, Toshinobu; Aramaki, Hideo; Nakahiro, Hideki; Nishiguchi, Ikuzo
Tetrahedron, 1996 , vol. 52, # 6 p. 1943 - 1952
反应条件
tetrabutylammomium bromide; oxygen; Azobenzene in acetonitrile
7 h; Ambient temperatureelectrolysis;
参考文献
Monte, William T.; Baizer, Manuel M.; Little, R. Daniel
Journal of Organic Chemistry, 1983 , vol. 48, # 6 p. 803 - 806
反应条件
1: diethylzinc; acetoacetic acid methyl ester in hexane; dichloromethane
T=0°C; 0.166667 h;
2: 1,1-Diiodoethane in hexane; dichloromethane
T=20°C; 1 h; Further stages.;
参考文献
Lin, Weimin; McGinness, Robert J.; Wilson, Emerald C.; Zercher, Charles K.
Synthesis, 2007 , # 15 p. 2404 - 2408
反应条件
tetraethylammonium p-toluenesulfonate in N,N-dimethyl-formamide
cathodic reduction;
参考文献
Shono, Tatsuya; Matsumura, Yoshihiro; Kashimura, Shigenori
Journal of Chemical Research, Miniprint, 1984 , # 7 p. 1922 - 1935
反应条件
in diethyl ether
T=-78°C; 6 h;
参考文献
Rakshit, Devajyoti; Thomas, Susan E.
Journal of Organometallic Chemistry, 1987 , vol. 333, p. C3 - C5
反应条件
air
T=25°C; 3 h; Irradiationother substrates; Mechanism;
参考文献
Macias, Francisco A.; Molinillo, Jose Maria G.; Collado, Isidro G.; Massanet, Guillermo M.; Rodriguez-Luis, Francisco
Tetrahedron Letters, 1990 , vol. 31, # 21 p. 3063 - 3066
Title/Abstract Full Text View citing articles Show Details
Macias; Molinillo; Massanet; Rodriguez-Luis
Tetrahedron, 1992 , vol. 48, # 16 p. 3345 - 3352
参考文献
Corey,E.J.; Hegedus,L.S.
Journal of the American Chemical Society, 1969 , vol. 91, p. 4926 - 4928
反应条件
1: aq. HBr
2: diethyl ether
View Scheme
参考文献
Atkins,R.C.; Trost,B.M.
Journal of Organic Chemistry, 1972 , vol. 37, p. 3133 - 3139
反应条件
in diethyl ether
T=20°C; 1 h;
参考文献
Kashima, Choji; Shirahata, Yoshie; Tsukamoto, Yoshihiro
Heterocycles, 2001 , vol. 54, # 1 p. 309 - 317
反应条件
1: 1) n-BuLi / 1) THF, 0 degC, 2) THF, -78 degC, 30 min
2: TFA / 5 h / 20 °C
3: (CO2H)2 / H2O; diethyl ether / 12 h / 20 °C
View Scheme
参考文献
Baldwin, Jack E.; Adlington, Robert M.; Bottaro, Jeffrey C.; Jain, Ashok U.; Kolhe, Jayant N.; et al.
Journal of the Chemical Society, Chemical Communications, 1984 , # 16 p. 1095 - 1096
