5-碘-1,2,3-三甲氧基苯合成路线 （共 37 条）
反应条件
copper bronze
1.) 240 deg C, 0.5 h, 2.) from 240 deg C to 280 deg C, 0.5 h; Further byproducts given;
参考文献
Bowden, Bruce F.; Read, Roger W.; Taylor, Walter C.
Australian Journal of Chemistry, 1981 , vol. 34, # 4 p. 799 - 817
反应条件
tin; copper
(heating);
参考文献
Stjernstroem,N.E.; Tengedal,J.E.
Acta Chemica Scandinavica (1947-1973), 1970 , vol. 24, p. 338 - 340
反应条件
tin; copper
(heating);
参考文献
Stjernstroem,N.E.; Tengedal,J.E.
Acta Chemica Scandinavica (1947-1973), 1970 , vol. 24, p. 338 - 340
反应条件
1: With piperidine; copper(l) iodide; bis-triphenylphosphine-palladium(II) chloride in tetrahydrofuran
T=20°C;
2: With potassium carbonate in methanol
T=0°C; 2 h;
参考文献
Provot, Olivier; Giraud, Anne; Peyrat, Jean-Francois; Alami, Mouad; Brion, Jean-Daniel
Tetrahedron Letters, 2005 , vol. 46, # 49 p. 8547 - 8550
反应条件
1: Pd2(PPh3)2Cl2; copper(l) iodide; N-ethyl-N,N-diisopropylamine / tetrahydrofuran / 1 h / 20 °C
2: potassium carbonate / methanol / 3 h / 20 °C
View Scheme
参考文献
Agabekov, Vladislav; Seiche, Wolfgang; Breit, Bernhard
Chemical Science, 2013 , vol. 4, # 6 p. 2418 - 2422
反应条件
1.1: copper(I) oxide; copper; potassium carbonate / diethylene glycol dimethyl ether / 5 h / Reflux
2.1: Eaton's reagent / 0.83 h / 80 °C
3.1: sodium hydride / tetrahydrofuran; mineral oil / 0 °C / Inert atmosphere
3.2: 2 h / 20 °C / Inert atmosphere
4.1: hydrogenchloride / ethanol; water / 12 h / Reflux
View Scheme
参考文献
Pal, Chinmay; Kundu, Milan Kumar; Bandyopadhyay, Uday; Adhikari, Susanta
Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 12 p. 3563 - 3567
反应条件
copper(l) iodide; caesium carbonate in 1,4-dioxane
T=25°C; 28 h;
参考文献
Yip, Sau Fan; Cheung, Hong Yee; Zhou, Zhongyuan; Kwong, Fuk Yee
Organic Letters, 2007 , vol. 9, # 17 p. 3469 - 3472
