1-吲哚-2,3-二甲氧基苯合成路线 （共 13 条）
反应条件
boron tribromide in dichloromethane T=-80 - 20°C; Inert atmosphere;
参考文献
Venkatesan, Koushik; Kouwer, Paul H. J.; Yagi, Shigeyuki; Mueller, Peter; Swager, Timothy M.
Journal of Materials Chemistry, 2008 , vol. 18, # 4 p. 400 - 407
反应条件
1: 1-iodo-2,3-dimethoxybenzene With boron tribromide in dichloromethane T=-78 - 20°C; Inert atmosphere; 2: diiodomethane With caesium carbonate in N,N-dimethyl-formamide T=120°C; 1 h; Inert atmosphere;
参考文献
Baba, Masanori; Hashimoto, Yuichi; Aoyama, Hiroshi; Sugita, Kazuyuki; Nakamura, Masahiko; Aoyama, Atsushi; Urata, Yasuo
Patent: US2012/316342 A1, 2012 ;
Location in patent: Page/Page column 24 ;
反应条件
sodium periodate; sulfuric acid; dihydrogen peroxide in ethanol; water
T=50°C; 0.5 h;
参考文献
Sathiyapriya
Asian Journal of Chemistry, 2011 , vol. 23, # 1 p. 41 - 43
反应条件
1: With 2,2,6,6-tetramethyl-piperidine; n-butyllithium; cobalt(II) dibromide in tetrahydrofuran; hexane
T=0 - 20°C; 0.5 h;
2: With iodine in tetrahydrofuran; hexane
T=20°C; 2 h;
3: With water; sodium thiosulfate in tetrahydrofuran; hexane
参考文献
Dayaker, Gandrath; Chevallier, Floris; Gros, Philippe C.; Mongin, Florence
Tetrahedron, 2010 , vol. 66, # 46 p. 8904 - 8910
反应条件
Oxonereg;; potassium iodide in methanol
T=20°C; 24 h;
参考文献
Narender; Srinivasu; Kulkarni; Raghavan
Synthetic Communications, 2002 , vol. 32, # 15 p. 2319 - 2324
反应条件
1: 1,2-dimethoxy-benzene With n-butyllithium in tetrahydrofuran
T=-78 - 20°C; 1 h;
2: 4,5-dihydro-5-(iodomethyl)furan-2(3H)-pne T=-78 - -10°C;
参考文献
Harrowven, David C; Nunn, Michael I.T; Fenwick, David R
Tetrahedron Letters, 2001 , vol. 42, # 42 p. 7501 - 7502
反应条件
sulfuric acid; potassium iodide
Diazotization;
参考文献
Chien; Adams
Journal of the American Chemical Society, 1934 , vol. 56, p. 1787,1790
Full Text Show Details
Mauthner
Journal fuer Praktische Chemie (Leipzig), 1937 , vol. <2> 149, p. 324,325
反应条件
1: K2CO3; xylene; diethylamine
2: iron; aqueous hydrochloric acid
3: aqueous H2SO4; KI / Diazotization
View Scheme
参考文献
Chien; Adams
Journal of the American Chemical Society, 1934 , vol. 56, p. 1787,1790
反应条件
1: iron; aqueous hydrochloric acid
2: aqueous H2SO4; KI / Diazotization
View Scheme
参考文献
Chien; Adams
Journal of the American Chemical Society, 1934 , vol. 56, p. 1787,1790
反应条件
1: H2, KOH / Raney-Ni / methanol
2: (i) NaNO2, aq. HCl, (ii) aq. KI
View Scheme
参考文献
Horner,L.; Weber,K.-H.
Chemische Berichte, 1963 , vol. 96, p. 1568 - 1578
