1-溴-2,5-二甲氧基苯合成路线 （共 45 条）
反应条件
1: copper-powder / 200 °C
2: aluminium chloride; carbon disulfide
3: aqueous hydriodic acid; phenol
4: acetone; diethyl ether
View Scheme
参考文献
Tanase
Yakugaku Zasshi, 1941 , vol. 61, p. 341,346
反应条件
potassium hydroxide
T=-7°C; 16 h; anodic oxidation;
参考文献
Gautier; Lewis; McKillop; Taylor
Synthetic Communications, 1994 , vol. 24, # 20 p. 2989 - 3008
反应条件
lithium diisopropyl amide
1.) THF, hexane, -78 deg C, 10 min, 2.) THF, hexane, from -40 deg C to RT, 2 h; Yield given. Multistep reaction;
参考文献
Khanapure; Reddy; Biehl
Journal of Organic Chemistry, 1987 , vol. 52, # 26 p. 5685-5690
反应条件
air; lithium diisopropyl amide
1.) THF, -70 - -60 deg C, 2.) THF, 20 deg C, 22 h; Yield given. Multistep reaction;
参考文献
Dodsworth, David J.; Calcagno, Maria-Pia; Ehrmann, E. Ursula; Devadas, Bhatt; Sammes, Peter G.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1981 , p. 2120 - 2124
反应条件
[2,2']bipyridinyl; Fe/Cr/Ni in N,N-dimethyl-formamide
Nozaki-Hiyama-Kishi reaction; Electrolysis;
参考文献
Durandetti; Nedelec; Perichon
Organic letters, 2001 , vol. 3, # 13 p. 2073 - 2076
