3-乙基-1-甲基-1,3-二氢-2H-吲哚-2-酮合成路线 （共 8 条）
反应条件
Pd(PCy3)2(H)(H2O)+BF4-; hydrogen; 1,4-di(diphenylphosphino)-butane in toluene
T=140°C; P=31028.9 Torr; 48 h; Yield given. Yields of byproduct given;
参考文献
El Ali, Bassam; Okuro, Kazumi; Vasapollo, Giuseppe; Alper, Howard
Journal of the American Chemical Society, 1996 , vol. 118, # 18 p. 4264 - 4270
反应条件
1: 1-methyl-1H-indole With tert.-butyl lithium
2: triethyl borane
3: (2E)-N-(2-iodophenyl)-N-methylbut-2-enamide With tris(dibenzylideneacetone)dipalladium(0) chloroform complex in tetrahydrofuran
0.5 h; Heating;
参考文献
Ishikura, Minoru; Takahashi, Norinobu; Yamada, Koji; Yanada, Reiko
Tetrahedron, 2006 , vol. 62, # 50 p. 11580 - 11591
反应条件
ReH7(PCy3)2; lithium chloride
T=150°C; Inert atmosphere;
参考文献
Jin, Hongming; Xie, Jin; Pan, Changduo; Zhu, Zhengbo; Cheng, Yixiang; Zhu, Chengjian
ACS Catalysis, 2013 , vol. 3, # 10 p. 2195 - 2198
反应条件
2: NaH / dimethylsulfoxide
3: 23 percent / n-Bu3SnH, AIBN / toluene / 24 h / Heating
View Scheme
参考文献
Bowman, W. Russell; Heaney, Harry; Jordan, Benjamin M.
Tetrahedron Letters, 1988 , vol. 29, # 50 p. 6657 - 6660
反应条件
sodium methylate
T=130°C;
参考文献
Brunner
Monatshefte fuer Chemie, 1897 , vol. 18, p. 533
反应条件
1: 94 percent / NaH / tetrahydrofuran / Ambient temperature
2: 72 percent / tri-n-butylstannane, AIBN / toluene / Heating
View Scheme
参考文献
Jones, Keith; Thompson, Mervyn; Wright, Colin
Journal of the Chemical Society, Chemical Communications, 1986 , # 2 p. 115 - 116
反应条件
1: 84 percent / diethyl ether / 0 °C
2: 94 percent / NaH / tetrahydrofuran / Ambient temperature
3: 72 percent / tri-n-butylstannane, AIBN / toluene / Heating
View Scheme
参考文献
Jones, Keith; Thompson, Mervyn; Wright, Colin
Journal of the Chemical Society, Chemical Communications, 1986 , # 2 p. 115 - 116
参考文献
Rutenberg; Horning
Org.Synth.Coll.Vol., 1963 , vol. IV, p. 620
