8-(4-氯苯基)-1,4-二噁螺[4.5]癸烷合成路线 （共 7 条）
反应条件
hydrogen; palladium on activated charcoal in ethyl acetate 3 h;
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 15, # 22 p. 4910 - 4914
反应条件
1: TsOH / benzene / Heating 2: H2 / Pd/C / ethyl acetate / 3 h View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 15, # 22 p. 4910 - 4914
反应条件
1: 83 percent / tBuLi / tetrahydrofuran / -60 °C 2: 75 percent / P2I4 View Scheme
参考文献
Tetrahedron Letters, , vol. 39, # 42 p. 7629 - 7632
反应条件
1.1: magnesium / tetrahydrofuran / |Reflux 1.2: 20 °C / |Reflux 2.1: pyridine; 1,8-diazabicyclo[5.4.0]undec-7-ene; trichlorophosphate / 0 - 80 °C 3.1: palladium 10 on activated carbon; hydrogen / methanol; ethyl acetate / 5 h / 30003 Torr View Scheme
参考文献
Journal of the American Chemical Society, , vol. 134, # 41 p. 17023 - 17026,4
反应条件
diphosphorous tetraiodide
参考文献
Williams, David R.; Clark, Michael P.
Tetrahedron Letters, 1998 , vol. 39, # 42 p. 7629 - 7632
反应条件
1: 83 percent / tBuLi / tetrahydrofuran / -60 °C 2: 75 percent / P2I4 View Scheme
参考文献
Tetrahedron Letters, , vol. 39, # 42 p. 7629 - 7632
反应条件
toluene-4-sulfonic acid in water; acetone T=70°C; 3 h;
参考文献
Roy, Bhairab N; Singh, Girij P; Lathi, Piyush S; Agrawal, Manoj K; Mitra, Rangan; Trivedi, Anurag
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2013 , vol. 52, # 10 p. 1299 - 1312
