(3S,4S)-N-Boc-3-苄氨基-4-羟基吡咯烷合成路线 （共 6 条）
反应条件
water; potassium carbonate
参考文献
GAVARDINAS, Konstantinos; Jadhav, Prabhakar Kondaji
Patent: US2009/163472 A1, 2009 ;
Location in patent: Page/Page column 25 ;
US 20090163472 A1
反应条件
1.1: methanol / 15 h / 20 °C 2.1: m-CPBA / CH2Cl2 / 48 h / 20 °C 3.1: 1.29 kg / H2O / 5 h / 20 - 65 °C 4.1: (+)-mandelic acid / acetonitrile; H2O 4.2: 39 percent / 3 percent K2CO3 View Scheme
参考文献
Tetrahedron Asymmetry, , vol. 12, # 21 p. 2989 - 2997
反应条件
1.1: 60 percent / NaH / dimethylformamide / 5.67 h / 20 - 50 °C 2.1: m-CPBA / CH2Cl2 / 48 h / 20 °C 3.1: 1.29 kg / H2O / 5 h / 20 - 65 °C 4.1: (+)-mandelic acid / acetonitrile; H2O 4.2: 39 percent / 3 percent K2CO3 View Scheme
参考文献
Tetrahedron Asymmetry, , vol. 12, # 21 p. 2989 - 2997
反应条件
1.1: m-CPBA / CH2Cl2 / 48 h / 20 °C 2.1: 1.29 kg / H2O / 5 h / 20 - 65 °C 3.1: (+)-mandelic acid / acetonitrile; H2O 3.2: 39 percent / 3 percent K2CO3 View Scheme
参考文献
Tetrahedron Asymmetry, , vol. 12, # 21 p. 2989 - 2997
反应条件
1.1: 1.29 kg / H2O / 5 h / 20 - 65 °C 2.1: (+)-mandelic acid / acetonitrile; H2O 2.2: 39 percent / 3 percent K2CO3 View Scheme
参考文献
Tetrahedron Asymmetry, , vol. 12, # 21 p. 2989 - 2997
反应条件
hydrogen; palladium on activated charcoal in ethanol T=40°C; 5 h;
参考文献
Tsuzuki, Yasunori; Chiba, Katsumi; Mizuno, Kazuhiro; Tomita, Kyoji; Suzuki, Kenji
Tetrahedron Asymmetry, 2001 , vol. 12, # 21 p. 2989 - 2997
