2-(4-氟苄基)丙二酸二甲酯合成路线 （共 3 条）
反应条件
1: malonic acid dimethyl ester With sodium in methanol 0.5 h; 2: 4-bromomethyl-fluorobenzene in methanol 2 h; Heating / reflux;
参考文献
US2003/236230 A1, ;
Page 35; 37 ;
US 20030236230 A1
反应条件
sodium methylate in methanol Alkylation; 5 h; Heating;
参考文献
Boiadjiev, Stefan E.; Lightner, David A.
Journal of Physical Organic Chemistry, 1999 , vol. 12, # 10 p. 751 - 757
反应条件
1: NaOH / methanol; H2O / 3 h / Heating 2: 1 h / 145 - 150 °C View Scheme
参考文献
Boiadjiev, Stefan E.; Lightner, David A.
Journal of Physical Organic Chemistry, 1999 , vol. 12, # 10 p. 751 - 757
