1-N-Boc-3-碘甲基哌啶合成路线 (共 5 条)
反应条件
1H-imidazole; iodine; triphenylphosphine in benzene T=20°C; 3 h;
参考文献
KYORIN PHARMACEUTICAL CO., LTD.
Patent: EP1780210 A1, 2007 ;
Location in patent: Page/Page column 54-55 ;
反应条件
sodium iodide in acetone T=80°C; 2 h;
参考文献
WO2007/115058 A2, ;
Page/Page column 108 ;
WO 2007/115058 A2
反应条件
1: tetrahydrofuran 2: LAH / tetrahydrofuran 3: I2; PPh3; imidazole / CH2Cl2 View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 12, # 21 p. 3235 - 3238
反应条件
1: LAH / tetrahydrofuran 2: I2; PPh3; imidazole / CH2Cl2 View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 12, # 21 p. 3235 - 3238
反应条件
1: tetrahydrofuran 2: LAH / tetrahydrofuran 3: I2; PPh3; imidazole / CH2Cl2 View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 12, # 21 p. 3235 - 3238