253185-03-4合成路线 （共 388 条）
反应条件
bromine; chlorine in monofluoro-trichloromethane
T=10°C; 0.0333333 h; Irradiation; Yield given;
参考文献
Skell, P. S.; Baxter, H. N.; Tanko, J. M.
Tetrahedron Letters, 1986 , vol. 27, # 43 p. 5181 - 5184
反应条件
1: (i) SOCl2, (ii) /BRN= 1421537/, AlCl3
2: (i) LiAlH4, (ii) H2SO4
View Scheme
参考文献
Haynes,J.K.; Kampmeier,J.A.
Journal of Organic Chemistry, 1972 , vol. 37, # 25 p. 4167 - 4172
反应条件
1: (bromination)
2: (i) Mg, (ii) /BRN= 1900390/
View Scheme
参考文献
Akkerman,O.S.
Recueil des Travaux Chimiques des Pays-Bas, 1967 , vol. 86, p. 1018 - 1024
参考文献
Wenz, Gerhard; Strassnig, Christian; Thiele, Carolin; Engelke, Annegret; Morgenstern, Bernd; Hegetschweiler, Kaspar
Chemistry - A European Journal, 2008 , vol. 14, # 24 p. 7202 - 7211
反应条件
aluminium trichloride in dichloromethane
18 h; Ambient temperature;
参考文献
Wienk, Martijn M.; Janssen, Rene A. J.
Journal of the American Chemical Society, 1997 , vol. 119, # 23 p. 5398 - 5403
反应条件
1: 50 percent / AlCl3 / nitromethane
2: 62 percent / AlCl3 / CH2Cl2
3: NH2OH*HCl; pyridine / ethanol
View Scheme
参考文献
Farmer, Luc J.; Marron, Kristen S.; Canan Koch, Stacie S.; Hwang; Kallel, E. Adam; Zhi, Lin; Nadzan, Alex M.; Robertson, Dave W.; Bennani, Youssef L.
Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 9 p. 2352 - 2356
反应条件
T=-196.1°C; P=5E-05 Torr;
参考文献
Armstrong, Brian M.
Journal of the American Chemical Society, 1998 , vol. 120, # 24 p. 6007 - 6011
反应条件
1: 74 percent / AlCl3 / CH2Cl2 / 18 h / Ambient temperature
2: 97 percent / LiAlH4 / tetrahydrofuran / 0.5 h / Ambient temperature
3: 93 percent / PBr3 / toluene / 1 h / Ambient temperature
View Scheme
参考文献
Wienk, Martijn M.; Janssen, Rene A. J.
Journal of the American Chemical Society, 1997 , vol. 119, # 23 p. 5398 - 5403
反应条件
calcium; ammonium chloride
1.) methylamine, ethylenediamine, 22h, 2.) 0 deg C, diethyl ether; Yield given. Yields of byproduct given;
参考文献
Benkeser, Robert A.; Belmonte, Frank G.; Kang, Jahyo
Journal of Organic Chemistry, 1983 , vol. 48, # 17 p. 2796 - 2802
反应条件
4 Aequivalente Lithium;
参考文献
Benkeser et al.
Journal of Organic Chemistry, 1959 , vol. 24, p. 854
