(R)-(-)-3-奎宁醇合成路线 （共 33 条）
反应条件
potassium tert-butylate; hydrogen; RuCl2[(S,S)-xylskewphos] (dmf)n in ethanol T=30°C; P=7600.51 Torr; 19 h; Product distribution / selectivity;
参考文献
EP1867654 A1, ;
Page/Page column 30 ;
反应条件
sodium hydroxide; water in methanol T=50°C; 10 h;
参考文献
US2005/137203 A1, ;
Page/Page column 19 ;
US 20050137203 A1
反应条件
hydrogen; (S)-1-[(R)-1',2- bis (diphenylphosphino) ferrocenyl] ethanol; 1,5-cyclooctadienerhodium (I) chloride dimer; (1R,2R)-(+)-1,2-diphenylethylenediamine in ethanol T=30°C; P=26252.6 Torr; 16 h; Product distribution / selectivity;
参考文献
WO2004/78686 A1, ;
Page 14, 15 ;
反应条件
D-glucose in aq. phosphate buffer T=37°C; pH=8; 30 h; ConcentrationTemperaturepH-valueTime;
参考文献
Journal of Molecular Catalysis B: Enzymatic, , vol. 88, p. 14 - 19
反应条件
sodium hydroxide T=50°C; 1 h;
参考文献
Synthetic Communications, , vol. 22, # 13 p. 1895 - 1911
反应条件
sodium carbonate in methanol T=65°C; 16 h;
参考文献
Tetrahedron Asymmetry, , vol. 14, # 13 p. 1871 - 1877
反应条件
camphor-10-sulfonic acid
参考文献
Journal of the American Chemical Society, , vol. 74, p. 2219
反应条件
Aspergillus melleus protease in phosphate buffer T=25°C; pH=7.5; 16 h; Title compound not separated from byproducts;
参考文献
Tetrahedron Asymmetry, , vol. 14, # 13 p. 1871 - 1877
反应条件
1: potassium; toluene / anschliessend mit konz. Salzsaeure 2: lithium alanate; diethyl ether 3: (1S)-2-oxo-bornane-10-sulfonic acid View Scheme
参考文献
Journal of the American Chemical Society, , vol. 74, p. 2219
反应条件
1: With acetic anhydride T=160°C; 3 h; 2: With sodium hydroxide T=75°C; 2 h;
参考文献
Synthetic Communications, , vol. 36, # 13 p. 1815 - 1822
