反应条件
1.1: triethylamine / dichloromethane / 1 h / 20 °C / Inert atmosphere
2.1: 1,8-diazabicyclo[5.4.0]undec-7-ene / dichloromethane / 1 h / Inert atmosphere
3.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 3 h
4.1: Dess-Martin periodane / dichloromethane / 2 h
5.1: sodium dihydrogenphosphate; sodium chlorite; 2-methyl-but-2-ene / tetrahydrofuran; water / 2 h
5.2: pH 2
6.1: BOP-Cl; triethylamine / acetonitrile / Inert atmosphere
7.1: lithium hydroxide hydrate / tetrahydrofuran; water / 2 h / 20 °C
7.2: pH 3
8.1: dichloromethane / 2 h / 20 °C
9.1: diphenyl phosphoryl azide / N,N-dimethyl-formamide / 2 h / 20 °C
View Scheme
参考文献
Aulakh, Virender S.; Ciufolini, Marco A.
Journal of the American Chemical Society, 2011 , vol. 133, # 15 p. 5900 - 5904