氰甲基磷酸二乙酯合成路线

256431-72-8(E)-3-[2-环丙基-4-(4-氟苯基)-3-喹啉基]-2-丙烯腈

参考文献

Suzuki; Iwasaki; Fujikawa; Kitahara; Sakashita; Sakoda
Bioorganic and Medicinal Chemistry, 2001 , vol. 9, # 10 p. 2727 - 2743

2537-48-6氰甲基磷酸二乙酯+

121660-37-52-环丙基-4-(4-氟苯基)喹啉-3-甲醛

256431-72-8(E)-3-[2-环丙基-4-(4-氟苯基)-3-喹啉基]-2-丙烯腈

参考文献

Suzuki, Mikio; Yanagawa, Yoshinobu; Iwasaki, Hiroshi; Kanda, Hiroyasu; Yanagihara, Kazufumi; Matsumoto, Hiroo; Ohara, Yoshio; Yazaki, Yukari; Sakoda, Ryozo
Bioorganic and Medicinal Chemistry Letters, 1999 , vol. 9, # 20 p. 2977 - 2982

参考文献

Morton, Colin J.H; Gilmour, Ryan; Smith, David M; Lightfoot, Philip; Slawin, Alexandra M.Z; MacLean, Elizabeth J
Tetrahedron, 2002 , vol. 58, # 27 p. 5547 - 5565

2537-48-6氰甲基磷酸二乙酯+

555-16-8对硝基苯甲醛

27892-88-2

参考文献

Has-Becker; Bodmann; Kreuder; Santoni; Rein; Reiser
Synlett, 2001 , # 9 p. 1395 - 1398

2537-48-6氰甲基磷酸二乙酯+

196597-78-11,2,6,7-四氢-8H-茚并[5,4-b]呋喃-8-酮

196597-79-2(E)-(1,6,7,8-四氢-2H-茚并[5,4-b]呋喃-8-亚基)乙腈

参考文献

USV LIMITED; SATHE, Dhananjay, Govind; BHISE, Nandu, Baban; GATNE, Parag, Sukumar; PATNEKAR, Subodh, Shashikant; DEORE, Raviraj, Bhatu; MAHAJAN, Anil, Dinkar
Patent: WO2010/41271 A2, 2010 ;
Location in patent: Page/Page column 24 ;30 ;

196597-79-2(E)-(1,6,7,8-四氢-2H-茚并[5,4-b]呋喃-8-亚基)乙腈

参考文献

Ishida, Hajime; Fukuta, Makoto
Patent: US2004/18239 A1, 2004 ;

91-02-12-苯甲酰吡啶+

2537-48-6氰甲基磷酸二乙酯

参考文献

Ishikawa
Chemical and pharmaceutical bulletin, 1980 , vol. 28, # 5 p. 1394 - 1402

4746-97-81,4-环己二酮单乙二醇缩酮+

2537-48-6氰甲基磷酸二乙酯

124499-35-02-(1,4-二噁螺[4.5]-8-癸基)乙腈

参考文献

Tetrahedron, , vol. 51, # 37 p. 10259 - 10280

398489-26-41-Boc-3-氮杂环丁酮+

2537-48-6氰甲基磷酸二乙酯

1153949-11-13-(氰基亚甲基)氮杂丁烷-1-羧酸叔丁酯

参考文献

INCYTE CORPORATION
Patent: US2009/233903 A1, 2009 ;
Location in patent: Page/Page column 26-27; 58 ;
US 20090233903 A1

6704-31-03-氧杂环丁酮+

2537-48-6氰甲基磷酸二乙酯

1123787-67-62-(氧杂环丁烷-3-基)乙腈

参考文献

BIOCRYST PHARMACEUTICALS, INC.; BABU, Yarlagadda, S.; CHAND, Pooran; KOTIAN, Pravin, L.; KUMAR, V., Satish
Patent: WO2010/14930 A2, 2010 ;
Location in patent: Page/Page column 63 ;
WO 2010/014930 A2