(6CI,7CI,8CI,9CI)-吡啶并[3,4-b]吡嗪合成路线 (共 4 条)
反应条件
in ethanol; water T=110°C; 1 h; Inert atmosphereMicrowave irradiation;
参考文献
CALITOR SCIENCES, LLC; SUNSHINE LAKE PHARMA CO., LTD; XI, Ning; WANG, Ruyong; WANG, Liang
Patent: WO2014/89324 A1, 2014 ;
Location in patent: Paragraph 0302 ;
反应条件
acetic acid und Erhitzen des Reaktionsprodukts auf 240grad/15 Torr;
参考文献
Koenigs; Bueren; Jung
Chemische Berichte, 1936 , vol. 69, p. 2691
反应条件
N-bromosuccinmide in acetonitrile T=20°C; 16 h; DarknessInert atmosphere;
参考文献
Tandon, Raman; Unzner, Teresa; Nigst, Tobias A.; De Rycke, Nicolas; Mayer, Peter; Wendt, Bernd; David, Olivier R. P.; Zipse, Hendrik
Chemistry - A European Journal, 2013 , vol. 19, # 20 p. 6435 - 6442
反应条件
sodium tetrahydroborate; trifluoroacetic acid in tetrahydrofuran 1 h;
参考文献
Singh, Satwinder; Das, Goutam; Singh, Om V.; Han, Hyunsoo
Organic Letters, 2007 , vol. 9, # 3 p. 401 - 404