1.1: trichlorophosphate / 1,2-dichloro-benzene / 3 h / 70 °C / |Cooling with ice 2.1: dihydrogen peroxide; potassium dihydrogenphosphate; sodium chlorite / tetrahydrofuran; water / 8 h / 20 °C 3.1: thionyl chloride / chloroform / 6 h / |Reflux 4.1: potassium carbonate / tetrahydrofuran / 12 h / 20 °C 5.1: sodium hydride / tetrahydrofuran; mineral oil / 20.5 h / 50 °C / |Cooling with ice; |Inert atmosphere 6.1: palladium diacetate; silver(l) oxide; potassium acetate / N,N-dimethyl-formamide / 110 °C 7.1: lithium aluminium tetrahydride / diethyl ether / 3 h / 20 °C / |Cooling with ice 7.2: 0.5 h / |Cooling with ice 8.1: pyridine; trimethylsilyl iodide / sulfolane / 20 h / 70 °C / |Inert atmosphere 9.1: sodium hydroxide; oxygen / water; acetone / 18 h / 20 °C 10.1: hydrogenchloride / tetrahydrofuran / 20 h / 60 °C View Scheme

1.1: tetrahydrofuran / 1 h / 10 °C 2.1: N,N-dimethyl-formamide / 3 h / 20 °C / |Inert atmosphere 3.1: potassium carbonate / tetrahydrofuran / 24 h / 20 °C / |Inert atmosphere 3.2: 24 h / |Reflux; |Inert atmosphere 4.1: N-bromosuccinmide; 2,2'-azo-bisisobutyronitrile / tetrachloromethane / 2 h / |Inert atmosphere; |Reflux 5.1: tetra(n-butyl)ammonium dichromate(VI) / chloroform / 10 h / |Inert atmosphere; |Reflux 6.1: boron tribromide / dichloromethane / 0.08 h / 0 °C / |Inert atmosphere 7.1: sodium hydroxide / water; dimethyl sulfoxide / 3 h / 20 °C / |Inert atmosphere 8.1: palladium 10 on activated carbon; hydrogen / ethanol / 6 h / 20 °C 8.2: 1 h / 0 °C / |Inert atmosphere View Scheme

1.1: sodium hydroxide / water; dimethyl sulfoxide / 3 h / 20 °C / |Inert atmosphere 2.1: palladium 10 on activated carbon; hydrogen / ethanol / 6 h / 20 °C 2.2: 1 h / 0 °C / |Inert atmosphere View Scheme

1.1: N-bromosuccinmide; 2,2'-azo-bisisobutyronitrile / tetrachloromethane / 3 h / |Inert atmosphere; |Reflux 2.1: triphenylphosphine / tetrahydrofuran / 6 h / |Inert atmosphere; |Reflux 2.2: 24 h / 20 °C / |Inert atmosphere 3.1: phenyltrimethylammonium tribromide / tetrahydrofuran / 3 h / 20 °C / |Inert atmosphere 4.1: N,N-dimethyl-formamide / 3 h / 20 °C / |Inert atmosphere 5.1: potassium carbonate / tetrahydrofuran / 24 h / 20 °C / |Inert atmosphere 5.2: 24 h / |Reflux; |Inert atmosphere 6.1: N-bromosuccinmide; 2,2'-azo-bisisobutyronitrile / tetrachloromethane / 2 h / |Inert atmosphere; |Reflux 7.1: tetra(n-butyl)ammonium dichromate(VI) / chloroform / 10 h / |Inert atmosphere; |Reflux 8.1: boron tribromide / dichloromethane / 0.08 h / 0 °C / |Inert atmosphere 9.1: sodium hydroxide / water; dimethyl sulfoxide / 3 h / 20 °C / |Inert atmosphere 10.1: palladium 10 on activated carbon; hydrogen / ethanol / 6 h / 20 °C 10.2: 1 h / 0 °C / |Inert atmosphere View Scheme

1.1: triphenylphosphine / tetrahydrofuran / 6 h / |Inert atmosphere; |Reflux 1.2: 24 h / 20 °C / |Inert atmosphere 2.1: phenyltrimethylammonium tribromide / tetrahydrofuran / 3 h / 20 °C / |Inert atmosphere 3.1: N,N-dimethyl-formamide / 3 h / 20 °C / |Inert atmosphere 4.1: potassium carbonate / tetrahydrofuran / 24 h / 20 °C / |Inert atmosphere 4.2: 24 h / |Reflux; |Inert atmosphere 5.1: N-bromosuccinmide; 2,2'-azo-bisisobutyronitrile / tetrachloromethane / 2 h / |Inert atmosphere; |Reflux 6.1: tetra(n-butyl)ammonium dichromate(VI) / chloroform / 10 h / |Inert atmosphere; |Reflux 7.1: boron tribromide / dichloromethane / 0.08 h / 0 °C / |Inert atmosphere 8.1: sodium hydroxide / water; dimethyl sulfoxide / 3 h / 20 °C / |Inert atmosphere 9.1: palladium 10 on activated carbon; hydrogen / ethanol / 6 h / 20 °C 9.2: 1 h / 0 °C / |Inert atmosphere View Scheme

1.1: potassium carbonate / tetrahydrofuran / 12 h / 20 °C 2.1: phosphorous pentoxide; dimethylformaldehyde dimethyl acetal / chloroform / 8 h / 20 °C / |Inert atmosphere 3.1: palladium diacetate; silver(l) oxide; potassium acetate / N,N-dimethyl-formamide / 110 °C 4.1: lithium aluminium tetrahydride / diethyl ether / 3 h / 20 °C / |Cooling with ice 4.2: 0.5 h / |Cooling with ice 5.1: pyridine; trimethylsilyl iodide / sulfolane / 20 h / 70 °C / |Inert atmosphere 6.1: anhydrous iron chloride; tert.-butylhydroperoxide; pyridine-2,6-dicarboxylate N-oxide / water; 1,1-dimethylpropan-1-ol / 8 h / 20 °C / |Cooling with ice View Scheme

1.1: dihydrogen peroxide; potassium dihydrogenphosphate; sodium chlorite / tetrahydrofuran; water / 8 h / 20 °C 2.1: thionyl chloride / chloroform / 6 h / |Reflux 3.1: potassium carbonate / tetrahydrofuran / 12 h / 20 °C 4.1: phosphorous pentoxide; dimethylformaldehyde dimethyl acetal / chloroform / 8 h / 20 °C / |Inert atmosphere 5.1: palladium diacetate; silver(l) oxide; potassium acetate / N,N-dimethyl-formamide / 110 °C 6.1: lithium aluminium tetrahydride / diethyl ether / 3 h / 20 °C / |Cooling with ice 6.2: 0.5 h / |Cooling with ice 7.1: pyridine; trimethylsilyl iodide / sulfolane / 20 h / 70 °C / |Inert atmosphere 8.1: anhydrous iron chloride; tert.-butylhydroperoxide; pyridine-2,6-dicarboxylate N-oxide / water; 1,1-dimethylpropan-1-ol / 8 h / 20 °C / |Cooling with ice View Scheme

1.1: thionyl chloride / chloroform / 6 h / |Reflux 2.1: potassium carbonate / tetrahydrofuran / 12 h / 20 °C 3.1: phosphorous pentoxide; dimethylformaldehyde dimethyl acetal / chloroform / 8 h / 20 °C / |Inert atmosphere 4.1: palladium diacetate; silver(l) oxide; potassium acetate / N,N-dimethyl-formamide / 110 °C 5.1: lithium aluminium tetrahydride / diethyl ether / 3 h / 20 °C / |Cooling with ice 5.2: 0.5 h / |Cooling with ice 6.1: pyridine; trimethylsilyl iodide / sulfolane / 20 h / 70 °C / |Inert atmosphere 7.1: anhydrous iron chloride; tert.-butylhydroperoxide; pyridine-2,6-dicarboxylate N-oxide / water; 1,1-dimethylpropan-1-ol / 8 h / 20 °C / |Cooling with ice View Scheme

1.1: phosphorous pentoxide; dimethylformaldehyde dimethyl acetal / chloroform / 8 h / 20 °C / |Inert atmosphere 2.1: palladium diacetate; silver(l) oxide; potassium acetate / N,N-dimethyl-formamide / 110 °C 3.1: lithium aluminium tetrahydride / diethyl ether / 3 h / 20 °C / |Cooling with ice 3.2: 0.5 h / |Cooling with ice 4.1: pyridine; trimethylsilyl iodide / sulfolane / 20 h / 70 °C / |Inert atmosphere 5.1: anhydrous iron chloride; tert.-butylhydroperoxide; pyridine-2,6-dicarboxylate N-oxide / water; 1,1-dimethylpropan-1-ol / 8 h / 20 °C / |Cooling with ice View Scheme

1.1: trichlorophosphate / 10 - 20 °C / Inert atmosphere 1.2: 20 - 35 °C / Inert atmosphere 1.3: 30 °C / Cooling with ice; Inert atmosphere 2.1: N-bromosuccinmide / N,N-dimethyl-formamide / 20 °C / Inert atmosphere 3.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 0 - 20 °C / Inert atmosphere 3.2: 1 h / 20 °C / Inert atmosphere 4.1: copper(l) iodide / methanol; N,N-dimethyl-formamide / 10 h / 120 °C / Inert atmosphere 5.1: toluene-4-sulfonic acid / tetrahydrofuran / 0.25 h / Reflux; Inert atmosphere 6.1: triethylamine / dichloromethane / 2 h / 20 °C / Inert atmosphere 7.1: palladium diacetate; potassium carbonate; triphenylphosphine / N,N-dimethyl-formamide / 7 h / 120 °C / Inert atmosphere 8.1: ammonium cerium (IV) nitrate / water; acetonitrile / 2 h / 20 °C / Inert atmosphere 9.1: hydrogen; palladium(II) oxide hydrate / methanol / 4 h / 3102.97 Torr View Scheme