3-(4-甲氧基苯基)-丙酰胺合成路线 （共 30 条）
反应条件
hydrogen in ethanol T=20°C; P=760.051 Torr; 2 h; chemoselective reaction;
参考文献
Kantam, Mannepalli Lakshmi; Kishore, Ramineni; Yadav, Jagjit; Sudhakar, Medak; Venugopal, Akula
Advanced Synthesis and Catalysis, 2012 , vol. 354, # 4 p. 663 - 669
参考文献
Perez-Medrano, Arturo; Donnelly-Roberts, Diana L.; Honore, Prisca; Hsieh, Gin C.; Namovic, Marian T.; Peddi, Sridhar; Shuai, Qi; Wang, Ying; Faltynek, Connie R.; Jarvis, Michael F.; Carroll, William A.
Journal of Medicinal Chemistry, 2009 , vol. 52, # 10 p. 3366 - 3376
反应条件
tert-butyl-amphos chloride; sodium lauryl sulfate; sodium carbonate; [RhCl(η2:η2-cycloocta-1,5-diene)]2 in toluene T=80°C; Title compound not separated from byproducts;
参考文献
Lautens, Mark; Mancuso, John; Grover, Harpreet
Synthesis, 2004 , # 12 p. 2006 - 2014
反应条件
1: 86 percent / P-ph-phen*Pd(0), NaOAc / dimethylformamide; H2O / 12 h / 130 °C 2: H2 / 5percent Pd/C / ethanol / 12 h / 100 °C / 3040 Torr View Scheme
参考文献
Zhuangyu, Zhang; Yi, Pan; Hongwen, Hu; Tsi-yu, Kao
Synthetic Communications, 1990 , vol. 20, # 22 p. 3563 - 3574
反应条件
1.1: SOCl2 1.2: NH3 / H2O 2.1: 78 percent / AlCl3; cyclohexane / CH2Cl2 / 7 h / 25 °C View Scheme
参考文献
Koltunov, Konstantin Yu.; Walspurger, Stephane; Sommer, Jean
European Journal of Organic Chemistry, 2004 , # 19 p. 4039 - 4047
反应条件
thionyl chloride; chloroform nachfolgend Behandlung mit Natriumhydroxyd in Ammoniak;
参考文献
Barger; Walpole
Journal of the Chemical Society, 1909 , vol. 95, p. 1722
参考文献
Kindler; Peschke
Archiv der Pharmazie (Weinheim, Germany), 1932 , vol. 270, p. 353,359
反应条件
1: palladium; acetic acid / 55 °C / Hydrogenation 2: aqueous ammonia View Scheme
参考文献
Kindler; Peschke
Archiv der Pharmazie (Weinheim, Germany), 1932 , vol. 270, p. 353,359
反应条件
1: aq.-ethanolic KOH-solution 2: 210 °C / Erhitzen im Ammoniak-Strom View Scheme
参考文献
Kindler; Peschke
Archiv der Pharmazie (Weinheim, Germany), 1932 , vol. 270, p. 353,359
反应条件
1: sodium / Behandeln des mit Benzol und Aether versetzten Reaktionsgemisches mit Essigsaeure und wss. Salzsaeure 2: palladium; acetic acid / 55 °C / Hydrogenation 3: aqueous ammonia View Scheme
参考文献
Barger; Walpole
Journal of the Chemical Society, 1909 , vol. 95, p. 1722
