2-(氨基甲基)-1,3-噻唑-4-羧酸合成路线 （共 7 条）
反应条件
trifluoroacetic acid in dichloromethane
0.5 h;
参考文献
M. Martin, Lenore; Hu, Bi-Huang
Patent: US2006/161007 A1, 2006 ;
Location in patent: Page/Page column 9; Sheet 1 ;
反应条件
lithium hydroxide in tetrahydrofuran
T=0°C; 1 h;
参考文献
Bernhardt, Paul V; Comba, Peter; Fairlie, David P; Gahan, Lawrence R; Hanson, Graeme R; Loetzbeyer, Lutz
Chemistry (Weinheim an der Bergstrasse, Germany), 2002 , vol. 8, # 7 p. 1527 - 1536
参考文献
Bodanszky,M. et al.
Journal of the American Chemical Society, 1964 , vol. 86, p. 2478 - 2490
反应条件
hydrogenchloride in 1,4-dioxane
Heating;
参考文献
Cross,D.F.W. et al.
Journal of the Chemical Society, 1963 , p. 2143 - 2150
反应条件
hydrogenchloride in 1,4-dioxane
Heating;
参考文献
Cross,D.F.W. et al.
Journal of the Chemical Society, 1963 , p. 2143 - 2150
反应条件
(i) EtOH, (ii) aq. HCl; Multistep reaction;
参考文献
Brookes,P. et al.
Journal of the Chemical Society, 1960 , p. 925 - 931
反应条件
in tetrahydrofuran
T=20°C; 12 h;
参考文献
Bernhardt, Paul V; Comba, Peter; Fairlie, David P; Gahan, Lawrence R; Hanson, Graeme R; Loetzbeyer, Lutz
Chemistry (Weinheim an der Bergstrasse, Germany), 2002 , vol. 8, # 7 p. 1527 - 1536
