α-(三甲基硅氧基)苯乙腈合成路线 （共 67 条）
反应条件
lithium diisopropyl amide 1) -78 deg C, THF, 2) in 6 h to 0 deg C; Multistep reaction. Title compound not separated from byproducts;
参考文献
Huenig, Siegfried; Marschner, Claus
Chemische Berichte, 1990 , vol. 123, # 1 p. 107 - 114
反应条件
diethyl ether 4 h; Reflux;
参考文献
Lee, Hyeon-Kyu; Kang, Soyeong; Choi, Eun Bok
Journal of Organic Chemistry, 2012 , vol. 77, # 12 p. 5454 - 5460
反应条件
1: in diethyl ether 6 h; Heating; 2: With sulfuric acid in diethyl ether
参考文献
Toukoniitty, Esa; Maeki-Arvela, Paeivi; Kuzma, Marek; Villela, Alexandre; Kalantar Neyestanaki, Ahmad; Salmi, Tapio; Sjoeholm, Rainer; Leino, Reko; Laine, Ensio; Murzin, Dmitry Yu.
Journal of Catalysis, 2001 , vol. 204, # 2 p. 281 - 291
反应条件
4-methyl-1,3-dioxolan-2-one; hydrogenchloride in water 6 h; Reflux;
参考文献
North, Michael; Omedes-Pujol, Marta
Beilstein Journal of Organic Chemistry, 2010 , vol. 6, p. 1043 - 1055
反应条件
(i) LDA, THF, Et2O, (ii) /BRN= 605278/, (iii) (hydrolysis); Multistep reaction;
参考文献
Huenig,S.; Wehner,G.
Synthesis, 1975 , p. 180 - 182
反应条件
hydrogenchloride Yield given;
参考文献
Dhanoa; Bagley; Chang; Lotti; Chen; Kivlighn; Zingaro; Siegl; Chakravarty; Patchett; Greenlee
Journal of Medicinal Chemistry, 1993 , vol. 36, # 23 p. 3738 - 3742
反应条件
1: 1.) lithium diisopropylamide / 2.) 5 h 2: 2n HCl View Scheme
参考文献
Boche, Gernot; Bosold, Ferdinand; Niessner, Manfred
Tetrahedron Letters, 1982 , vol. 23, # 32 p. 3255 - 3256
反应条件
sodium tetrahydroborate 1.) ether, RT, 1 h, 2.) EtOH, -76 deg C; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Jackson, W. Roy; Jacobs, Howard A.; Jayatilake, Gamini S.; Matthews, Barry R.; Watson, Keith G.
Australian Journal of Chemistry, 1990 , vol. 43, # 12 p. 2045 - 2062
反应条件
sodium tetrahydroborate 1.) ether, RT, 1 h, 2.) EtOH, -76 deg C; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Jackson, W. Roy; Jacobs, Howard A.; Jayatilake, Gamini S.; Matthews, Barry R.; Watson, Keith G.
Australian Journal of Chemistry, 1990 , vol. 43, # 12 p. 2045 - 2062
反应条件
4-methyl-1,3-dioxolan-2-one; hydrogenchloride in water 6 h; Reflux;
参考文献
North, Michael; Omedes-Pujol, Marta
Beilstein Journal of Organic Chemistry, 2010 , vol. 6, p. 1043 - 1055
