(S)-2-氨基-3-(4-甲氧基苯基)-2-甲基丙酸乙酯合成路线 （共 6 条）
反应条件
hydrogen; palladium on activated charcoal in methanol T=20°C; 12 h;
参考文献
Harel, Tal; Rozen, Shlomo
Journal of Organic Chemistry, 2007 , vol. 72, # 17 p. 6500 - 6503
反应条件
1: 90 percent / aq. tetrabutylammonium hydroxide / CH2Cl2 / 48 h / 20 °C 2: 100 percent / H2 / Pd/C / methanol / 12 h / 20 °C View Scheme
参考文献
Harel, Tal; Rozen, Shlomo
Journal of Organic Chemistry, 2007 , vol. 72, # 17 p. 6500 - 6503
反应条件
1: F2; MeCN; H2O / CH2Cl2 / 0 °C 2: 90 percent / aq. tetrabutylammonium hydroxide / CH2Cl2 / 48 h / 20 °C 3: 100 percent / H2 / Pd/C / methanol / 12 h / 20 °C View Scheme
参考文献
Harel, Tal; Rozen, Shlomo
Journal of Organic Chemistry, 2007 , vol. 72, # 17 p. 6500 - 6503
反应条件
1: hydrogenchloride; water; zinc / methanol / 20 °C / Reflux 2: sodium periodate; sodium dichromate; sulfuric acid / water / 20 h / 20 °C 3: thionyl chloride / -10 - 20 °C / Reflux View Scheme
参考文献
Dietz, Friedrich R.; Prechter, Agnes; Groeger, Harald; Heinrich, Markus R.
Tetrahedron Letters, 2011 , vol. 52, # 6 p. 655 - 657
反应条件
1: iron sulphate heptahydrate / water; dimethyl sulfoxide / Inert atmosphere 2: hydrogenchloride; water; zinc / methanol / 20 °C / Reflux 3: sodium periodate; sodium dichromate; sulfuric acid / water / 20 h / 20 °C 4: thionyl chloride / -10 - 20 °C / Reflux View Scheme
参考文献
Dietz, Friedrich R.; Prechter, Agnes; Groeger, Harald; Heinrich, Markus R.
Tetrahedron Letters, 2011 , vol. 52, # 6 p. 655 - 657
反应条件
thionyl chloride T=-10 - 20°C; Reflux;
参考文献
Dietz, Friedrich R.; Prechter, Agnes; Groeger, Harald; Heinrich, Markus R.
Tetrahedron Letters, 2011 , vol. 52, # 6 p. 655 - 657
