1: 89 percent / NaOH / ethanol / 12 h 2: 93 percent / 2,6-lutidine / CH2Cl2 / 1 h 3: 82 percent / PdCl2(dppf) / dioxane / 3 h / 90 °C 4: 95 percent / HCl / tetrahydrofuran / 3 h / Heating 5: 100 percent / K2CO3 / propan-2-ol; CH2Cl2 / 5 h / 45 °C 6: 87 percent / AlCl3; NaCl / 0.08 h / 150 °C View Scheme

1: 89 percent / NaOH / ethanol / 12 h 2: 93 percent / 2,6-lutidine / CH2Cl2 / 1 h 3: 82 percent / PdCl2(dppf) / dioxane / 3 h / 90 °C 4: 95 percent / HCl / tetrahydrofuran / 3 h / Heating 5: 100 percent / K2CO3 / propan-2-ol; CH2Cl2 / 5 h / 45 °C 6: 87 percent / AlCl3; NaCl / 0.08 h / 150 °C 7: 69 percent View Scheme