甲基9,10-二溴硬脂酸酯合成路线 （共 15 条）
反应条件
bromine in chloroform
参考文献
Knapp, F. F.; Goodman, M. M.; Kabalka, G. W.; Sastry, K. A. R.
Journal of Medicinal Chemistry, 1984 , vol. 27, # 1 p. 94 - 97
反应条件
1: 29.6 g / diethyl ether / 2 h / Ambient temperature 2: 100 percent / Br2 / CHCl3 View Scheme
参考文献
Knapp, F. F.; Goodman, M. M.; Kabalka, G. W.; Sastry, K. A. R.
Journal of Medicinal Chemistry, 1984 , vol. 27, # 1 p. 94 - 97
反应条件
Iodine bromide in chloroform-d1 0.5 h; Title compound not separated from byproducts;
参考文献
Imming, Peter; Germershaus, Oliver
Archiv der Pharmazie, 2002 , vol. 335, # 9 p. 449 - 451
反应条件
aluminium trichloride; sodium azide; bromine Ambient temperature; Yield given. Title compound not separated from byproducts;
参考文献
Agarwal, Rajiv; Rauf, Abdul; Ahmad, M.; Osman, S. M.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1989 , vol. 28, # 1-11 p. 175 - 177
反应条件
aluminium trichloride; sodium azide; bromine Ambient temperature; Yield given. Title compound not separated from byproducts;
参考文献
Agarwal, Rajiv; Rauf, Abdul; Ahmad, M.; Osman, S. M.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1989 , vol. 28, # 1-11 p. 175 - 177
反应条件
potassium hydroxide in pentan-1-ol 4 h; Heating;
参考文献
Pissas, D.; Dais, Photis; Mikros, E.
Magnetic Resonance in Chemistry, 1994 , vol. 32, # 5 p. 263 - 275
反应条件
1: 95 percent / 1,8-diazabicyclo<5.4.0>undec-7-ene (DBU) / 12 h / 140 °C 2: 71 percent / LAH / diethyl ether / 4 h 3: 53 percent / KH, 1,3-diaminopropane / 3.5 h / 0 - 20 °C 4: 60 percent / CrO3, H2SO4 / acetone / 16 h / 10 °C View Scheme
参考文献
Knapp, F. F.; Goodman, M. M.; Kabalka, G. W.; Sastry, K. A. R.
Journal of Medicinal Chemistry, 1984 , vol. 27, # 1 p. 94 - 97
反应条件
1: KOH / pentan-1-ol / 4 h / Heating 2: LiAlH4 / tetrahydrofuran / 4 h / Heating View Scheme
参考文献
Knapp, F. F.; Goodman, M. M.; Kabalka, G. W.; Sastry, K. A. R.
Journal of Medicinal Chemistry, 1984 , vol. 27, # 1 p. 94 - 97
反应条件
sodium tetrahydroborate; nickel dichloride in methanol T=20°C; 0.25 h;
参考文献
Khurana, Jitender M.; Kandpal, Bhaskar M.; Kukreja, Gagan; Sharma, Purnima
Canadian Journal of Chemistry, 2006 , vol. 84, # 8 p. 1019 - 1023
反应条件
[Co(PPh3)3Cl] in benzene 1 h; Ambient temperature; Yield given. Yields of byproduct given;
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 32, # 5 p. 1840 - 1853
