1-甲氧基甲氧基-4-甲基苯; 4-(甲氧基甲氧基)甲苯合成路线 （共 12 条）
反应条件
sodium hydride in N,N-dimethyl-formamide T=20°C; 26 h;
参考文献
Soegel, Sebastian; Tokunaga, Norihito; Sasaki, Keigo; Okamoto, Kazuhiro; Hayashi, Tamio
Organic Letters, 2008 , vol. 10, # 4 p. 589 - 592
反应条件
toluene-4-sulfonic acid in dichloromethane 45 h;
参考文献
Quinkert, Gerhard; Billhardt, Uta-Maria; Jakob, Harald; Fischer, Gerd; Glenneberg, Juergen; et al.
Helvetica Chimica Acta, 1987 , vol. 70, p. 822 - 861
参考文献
Hoering; Baum
Patent: DE209608 ;
参考文献
Hayashi,S. et al.
Chemical and Pharmaceutical Bulletin, 1972 , vol. 20, p. 15 - 20
反应条件
1: 1.) n-butyllithium, TMEDA / 1.) ether, hexane, -20 deg C, 1 h, 2.) 1 h 2: 1.) LDA / 1.) hexane, THF, 15 min, 2.) -78 deg C, 3 h 3: 0.90 g / CH3CO2H / 6 h / Heating View Scheme
参考文献
Harvey; Cortez; Ananthanarayan; Schmolka
Journal of Organic Chemistry, 1988 , vol. 53, # 17 p. 3936 - 3943
反应条件
1: 1.) n-butyllithium, TMEDA / 1.) ether, hexane, -20 deg C, 1 h, 2.) 1 h 2: 1.) LDA / 1.) hexane, THF, 15 min, 2.) -78 deg C, 3 h 3: 80 percent / CH3CO2H / 6 h / Heating View Scheme
参考文献
Journal of Organic Chemistry, , vol. 53, # 17 p. 3936 - 3943
反应条件
[Ru(II)(2,2’-bipyridine)3]Cl2; carbon tetrabromide in acetonitrile T=20°C; Irradiation;
参考文献
Zhao, Yating; Li, Zhe; Yang, Chao; Lin, Run; Xia, Wujiong
Beilstein Journal of Organic Chemistry, 2014 , vol. 10, p. 622 - 627
反应条件
1: (i) nBuLi, Me2NCH2CH2NMe2, hexane, (ii) /BRN= 605365/, xylene, (iii) aq. HCl 2: (i) TsOH, MeOH, (ii) aq. HCl View Scheme
参考文献
Christensen,H.
Synthetic Communications, 1975 , vol. 5, p. 65 - 78
反应条件
1.1: 2,2,6,6-tetramethyl-piperidine; n-butyllithium; potassium tert-butylate / tetrahydrofuran; hexane / -78 °C / Inert atmosphere 1.2: Inert atmosphere 2.1: hydrogenchloride / water / Reflux; Inert atmosphere View Scheme
参考文献
Journal of the American Chemical Society, , vol. 133, # 6 p. 1698 - 1701
反应条件
N-bromosuccinmide; dibenzoyl peroxide in tetrachloromethane
参考文献
Terumo Kabushiki Kaisha
Patent: US5374641 A1, 1994 ;
