(R)-α-(氨基甲基)苄醇合成路线 （共 67 条）
反应条件
hydrogen; potassium carbonate; [Rh(R,R,S,S-DuanPhos)(nbd)]SbF6 in 2,2,2-trifluoroethanol T=20°C; P=7500.75 Torr; 12 h; Title compound not separated from byproducts.;
参考文献
Chemistry - A European Journal, , vol. 13, # 27 p. 7780 - 7784
反应条件
ammonia in water T=20°C; 2 h;
参考文献
Yu, Feng; Zhou, Ji-Ning; Zhang, Xi-Chang; Sui, Yao-Zong; Wu, Fei-Fei; Xie, Lin-Jie; S. C. Chan, Albert; Wu, Jing
Chemistry - A European Journal, 2011 , vol. 17, # 50 p. 14234 - 14240
反应条件
1: trans-RuCl2[(R)-xylbinap][(R)-daipen]; t-BuOK; H2 / propan-2-ol; 2-methyl-propan-2-ol / 20 h / 25 °C / 6080.41 Torr 2: KOH / H2O; ethanol / 8 h / 80 °C View Scheme
参考文献
Journal of the American Chemical Society, , vol. 122, # 27 p. 6510 - 6511
反应条件
1.1: acetyl chloride / methanol / 0 - 22 °C 1.2: 90 percent / aq. NH3 / methanol / cooling 2.1: 84 percent / LiAlH4 / tetrahydrofuran / Heating View Scheme
参考文献
Angewandte Chemie - International Edition, , vol. 45, # 9 p. 1432 - 1435
反应条件
ammonium hydroxide in water T=130°C; P=9000.72 Torr; microwave irradiation;
参考文献
Tetrahedron Letters, , vol. 43, # 14 p. 2581 - 2584
反应条件
trifluoroacetic acid in water T=25°C; 0.5 h; Yield given;
参考文献
Journal of Organic Chemistry, , vol. 48, # 13 p. 2294 - 2295
反应条件
chiral stationary phase including isopropyl-functionalized CF6 in methanol; acetic acid; triethylamine; acetonitrile T=20°C; Purification / work up;
参考文献
WO2010/148191 A2, ;
Page/Page column 45-49; 58 ;
反应条件
hydrogen; palladium on activated charcoal in methanol Title compound not separated from byproducts.;
参考文献
Journal of Organic Chemistry, , vol. 67, # 5 p. 1712 - 1715
反应条件
pyridoxal 5'-phosphate in dimethyl sulfoxide T=20°C; 89 h; Enzymatic reaction; Title compound not separated from byproducts.;
参考文献
Advanced Synthesis and Catalysis, , vol. 349, # 8-9 p. 1379 - 1386
反应条件
1: 45 percent / H2O / 24 h / 30 °C / Baker's yeast on montmorilonite K 10, sucrose 2: 95 percent / H2 / Pd/C View Scheme
参考文献
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, , vol. 31, # 12 p. 821 - 823
