(R)-α-(氨基甲基)苄醇合成路线 （共 67 条）
反应条件
1: sodium azide; potassium iodide / water; acetonitrile / 1 h / 60 °C / |Green chemistry 2: magnesium sulfate; NADPH; alcohol dehydrogenase KRED-P1-B10 / isopropyl alcohol; aq. phosphate buffer / 2 h / 30 °C / pH 7 / |Autoclave; |Green chemistry; |Enzymatic reaction 3: hydrogen; sodium hydroxide / water; aq. phosphate buffer / 4 h / 30 °C / 7500.75 Torr / pH 9 / |Green chemistry View Scheme
参考文献
Green Chemistry, , vol. 15, # 12 p. 3318 - 3331
反应条件
potassium hydroxide in methanol; water 40 h; Heating;
参考文献
Kanerva, Liisa T.; Rahiala, Katri; Vaenttinen, Eero
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1992 , # 14 p. 1759 - 1762
反应条件
tetra-n-butylammonium tetrafluoroborate in N,N-dimethyl-formamide; isopropyl alcohol Electrochemical reaction;
参考文献
Yadav, Ashok K.; Manju, Meera
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2006 , vol. 45, # 12 p. 2770 - 2772
反应条件
1: 97 percent / ammonia gas / methanol / 22 h 2: 78 percent / LiAlH / tetrahydrofuran / 1.) reflux, 8 h, 2.) r.t., overnight View Scheme
参考文献
Agricultural and Biological Chemistry, , vol. 53, # 1 p. 165 - 174
反应条件
1: 2-methyl-butan-2-ol / 72 h / 40 °C / lipase PS 2: KOH / methanol; H2O / 40 h / Heating View Scheme
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , # 14 p. 1759 - 1762
反应条件
1: silver(l) oxide / dichloromethane / 0 - 20 °C 2: yeast Saccharomyces cerevisiae View Scheme
参考文献
Synthesis, , # 2 art. no. P14610SS, p. 316 - 324
反应条件
1.1: sodium ethanolate / ethanol / 0.17 h / 20 °C 1.2: 1 h / 0 °C 2.1: silver(l) oxide / dichloromethane / 0 - 20 °C 3.1: yeast Saccharomyces cerevisiae View Scheme
参考文献
Synthesis, , # 2 art. no. P14610SS, p. 316 - 324
反应条件
1: (S)-P-Phos; phenyl silane; copper diacetate / toluene / 24 h / -20 °C 2: ammonia / water / 2 h / 20 °C View Scheme
参考文献
Chemistry - A European Journal, , vol. 17, # 50 p. 14234 - 14240
反应条件
phenyl-hydroxy-acetic acid
参考文献
Journal of Organic Chemistry, , vol. 8, p. 564,566
反应条件
potassium hydroxide in methanol; water 40 h; Heating; Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , # 14 p. 1759 - 1762
