1-羟基-3-甲基蒽-9,10-二酮合成路线 （共 22 条）
反应条件
1: BuLi/i-Pr2NH / tetrahydrofuran / - 20 deg C, 30 min, then rt., 12 h
2: 2.) 5percent HCl / 1.) toluene, 80-100 deg C, 12 h; 2.) MeOH, rt., 10 h
View Scheme
参考文献
Khan; Blessing; Schmidt
Synthesis, 1994 , # 3 p. 255 - 257
反应条件
aluminium trichloride; sodium chloride
T=165°C;
参考文献
Waldmann; Sellner
Journal fuer Praktische Chemie (Leipzig), 1938 , vol. <2> 150, p. 145,149
反应条件
in tetrahydrofuran
Ambient temperature;
参考文献
Savard, Jacques; Brassard, Paul
Tetrahedron, 1984 , vol. 40, # 18 p. 3455 - 3464
反应条件
hydrogenchloride
1.) toluene, 80-100 deg C, 12 h; 2.) MeOH, rt., 10 h; Yield given. Multistep reaction;
参考文献
Khan; Blessing; Schmidt
Synthesis, 1994 , # 3 p. 255 - 257
反应条件
chromium(VI) oxide; acetic acid
bis auf Siedetemperatur;
参考文献
Keimatsu; Hirano; Yoshikawa
Yakugaku Zasshi, 1931 , vol. 51, p. 909,912;dtsch.Ref.S.123
Chem. Zentralbl., 1932 , vol. 103, # I p. 942
反应条件
2: hydrobromic acid
View Scheme
参考文献
Keimatsu; Hirano; Tanabe
Yakugaku Zasshi, 1929 , vol. 49, p. 85
Chem. Zentralbl., 1929 , vol. 100, # II p. 1537
反应条件
T=165°C; in einer AlCl3-NaCl-Schmelze;
参考文献
Waldmann; Sellner
Journal fuer Praktische Chemie (Leipzig), 1938 , vol. <2> 150, p. 145,149
反应条件
triethylamine
1.) benzene, reflux, 12 h; 2.) reflux, 48 h; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Iwao, Masatomo; Kuraishi, Tsukasa
Bulletin of the Chemical Society of Japan, 1987 , vol. 60, # 11 p. 4051 - 4060
反应条件
triethylamine
1.) toluene, 0 deg C, 1 h; 2.) 0 deg C, 4 h; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Iwao, Masatomo; Kuraishi, Tsukasa
Bulletin of the Chemical Society of Japan, 1987 , vol. 60, # 11 p. 4051 - 4060
反应条件
triethylamine
1.) toluene, 0 deg C, 1 h; 2.) 0 deg C, 4 h; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Iwao, Masatomo; Kuraishi, Tsukasa
Bulletin of the Chemical Society of Japan, 1987 , vol. 60, # 11 p. 4051 - 4060
