1: With lithium hexamethyldisilazane in N,N-dimethyl-formamide T=-50 - 20°C; Julia-Kocienski type gem-difluoroolefination; Inert atmosphere; 2: With hydrogenchloride; water; ammonium chloride in N,N-dimethyl-formamide Inert atmosphere;
1: With C46H47Cl2N3O4PRe in 1,4-dioxane T=20°C; 2: With tetrabutyl ammonium fluoride in 1,4-dioxane T=20°C; optical yield given as percent ee;
参考文献
Nolin, Kristine A.; Ahn, Richard W.; Kobayashi, Yusuke; Kennedy-Smith, Joshua J.; Toste, F. Dean
Chemistry - A European Journal, 2010 , vol. 16, # 31 p. 9555 - 9562
ammonium acetate; magnesium in methanol; water T=20 - 25°C; Yield given. Yields of byproduct given;
参考文献
Micovic, Ivan V.; Ivanovic; Roglic, Goran M.; Kiricojevic, Vesna D.; Popovic, Jelena B.
Journal of the Chemical Society - Perkin Transactions 1, 1996 , # 3 p. 265 - 269
