N,N-二甲基-5-硝基-2-吡啶胺合成路线 （共 19 条）
参考文献
Tschitschibabin; Kirssanow
Chemische Berichte, 1928 , vol. 61, p. 1230
Zhurnal Russkago Fiziko-Khimicheskago Obshchestva, 1928 , vol. 60, p. 975
参考文献
Tschitschibabin; Kirssanow
Chemische Berichte, 1928 , vol. 61, p. 1230
Zhurnal Russkago Fiziko-Khimicheskago Obshchestva, 1928 , vol. 60, p. 975
反应条件
hydrogen; palladium 10 on activated carbon in methanol; ethyl acetate T=20°C; P=2327.23 Torr; 1.5 h;
参考文献
PFIZER PRODUCTS INC.
Patent: WO2008/4117 A1, 2008 ;
Location in patent: Page/Page column 112 ;
反应条件
1: 24 percent / MCPBA / CHCl3 / 720 h / Ambient temperature 2: 98 percent / (chloromethylene)dimethylammonium chloride / CHCl3 / 0.5 h / Heating View Scheme
参考文献
Endo, Takeshi; Zemlicka, Jiri
Journal of Organic Chemistry, 1988 , vol. 53, # 9 p. 1887 - 1894
反应条件
hydrogenchloride; palladium 10 on activated carbon in methanol; water P=1034.32 Torr; 2 h;
参考文献
WO2004/74283 A1, ;
Page 69 ;
WO 2004/074283 A1
反应条件
3-chloro-benzenecarboperoxoic acid in chloroform 30 h; Ambient temperature;
参考文献
Journal of Organic Chemistry, , vol. 53, # 9 p. 1887 - 1894
参考文献
Chemische Berichte, , vol. 61, p. 1230
Zhurnal Russkago Fiziko-Khimicheskago Obshchestva, , vol. 60, p. 975
反应条件
1: With hydrogen; palladium 10 on activated carbon in methanol T=20°C; 16 h; 2: With hydrogenchloride in 1,4-dioxane; methanol
参考文献
SMITHKLINE BEECHAM CORPORATION
Patent: WO2008/147831 A1, 2008 ;
Location in patent: Page/Page column 22-23 ;
WO 2008/147831 A1
反应条件
3-chloro-benzenecarboperoxoic acid in chloroform
30 h; Ambient temperature;
参考文献
Endo, Takeshi; Zemlicka, Jiri
Journal of Organic Chemistry, 1988 , vol. 53, # 9 p. 1887 - 1894
