2-氨基-2-o-(2-甲氧基乙基)腺苷酸合成路线 (共 4 条)
反应条件
potassium hydroxide in dimethyl sulfoxide T=20°C; 7 h;
参考文献
Taj, Shabbir Ali S.; Gurumurthy; Suresh; Narayanan; Meenakshi, S. Suman; Sanghvi, Yogesh S.
Nucleosides, Nucleotides and Nucleic Acids, 2003 , vol. 22, # 5-8 p. 1327 - 1330
反应条件
1: 2-Methoxyethyl methanesulphonate; 2,6-Diamino-9-(β-D-ribofuranosyl)-purine With sodium hydride; lithium bromide in dimethyl sulfoxide; N,N-dimethyl-formamide T=50 - 52°C; 3 h; 2: 2-Methoxyethyl methanesulphonate With potassium hydroxide in dimethyl sulfoxide 18 h; Further stages.;
参考文献
Sivets, Grigorii G.
Nucleosides, Nucleotides and Nucleic Acids, 2007 , vol. 26, # 10-12 p. 1237 - 1240
反应条件
potassium hydroxide in dimethyl sulfoxide T=20°C; 6 h;
参考文献
Taj, Shabbir Ali S.; Narayanan; Meenakshi, S. Suman; Sanghvi, Yogesh S.; Ross, Bruce S.; Ravikumar, Vasulinga T.
Nucleosides, Nucleotides and Nucleic Acids, 2008 , vol. 27, # 9 p. 1024 - 1033
反应条件
sodium phosphate buffer; adenosine deaminase pH=7.2;
参考文献
Taj, Shabbir Ali S.; Gurumurthy; Suresh; Narayanan; Meenakshi, S. Suman; Sanghvi, Yogesh S.
Nucleosides, Nucleotides and Nucleic Acids, 2003 , vol. 22, # 5-8 p. 1327 - 1330