4,5-二溴苯-1,2-二醇合成路线 （共 34 条）
参考文献
Knuutinen, J.; Kolehmainen, E.
Magnetic Resonance in Chemistry, 1990 , vol. 28, p. 315 - 317
反应条件
caesium carbonate in N,N-dimethyl-formamide T=110°C; 3 h;
参考文献
Fleming, Matthew J.; McManus, Helen A.; Rudolph, Alena; Chan, Walter H.; Ruiz, Jeremy; Dockendorff, Chris; Lautens, Mark
Chemistry - A European Journal, 2008 , vol. 14, # 7 p. 2112 - 2124
反应条件
caesium carbonate in N,N-dimethyl-formamide T=100°C; 3 h; Inert atmosphere;
参考文献
De, Subhadip; Chaudhuri, Saikat; Mishra, Sourabh; Mamtani, Himanshu; Bisai, Alakesh
Journal of the Indian Chemical Society, 2013 , vol. 90, # 10 p. 1871 - 1884
反应条件
potassium hydroxide; Aliquatreg; 336 T=120°C; 3 h;
参考文献
Hu, Mougang; Brasseur, Nicole; Zeki Yildiz; Van Lier, Johan E.; Leznoff, Clifford C.
Journal of Medicinal Chemistry, 1998 , vol. 41, # 11 p. 1789 - 1802
反应条件
potassium hydroxide in dimethyl sulfoxide T=-20°C; 8 h;
参考文献
Kalashnikova; Zhukov; Tomilova; Zefirov
Russian Chemical Bulletin, 2005 , vol. 54, # 9 p. 2094 - 2098
反应条件
1: potassium carbonate / acetone / 50 °C / |Inert atmosphere 2: n-butyllithium / toluene; tetrahydrofuran / 5 h / -78 - 20 °C / |Inert atmosphere View Scheme
参考文献
De, Subhadip; Chaudhuri, Saikat; Mishra, Sourabh; Mamtani, Himanshu; Bisai, Alakesh
Journal of the Indian Chemical Society, 2013 , vol. 90, # 10 p. 1871 - 1884
反应条件
1: 78 percent / K2CO3 / ethanol / 8 h / Heating 2: 60 percent / dimethylformamide / 21 h / Heating 3: 91 percent / H2 / 10 percent Pd-C / ethyl acetate / 4 h / 20 °C View Scheme
参考文献
Cabezon, Beatriz; Quesada, Ernesto; Esperanza, Sagrario; Torres, Tomas
European Journal of Organic Chemistry, 2000 , # 15 p. 2767 - 2775
反应条件
sodium methylate in N,N-dimethyl-formamide 1) 1h, r.t., 2) 3h, 110 deg C;
参考文献
Molecular Crystals and Liquid Crystals (1969-1991), , vol. 187, p. 365 - 382
反应条件
potassium carbonate in N,N-dimethyl-formamide T=20°C; 16 h; Inert atmosphereCooling with ice;
参考文献
Zhang, Han-Cheng; Maryanoff, Bruce; White, Kimberly; Yabut, Stephen C.; Ye, Hong; Chen, Cailin
Patent: US2011/105490 A1, 2011 ;
Location in patent: Page/Page column 27 ;
US 20110105490 A1
反应条件
1: 54 percent / KOH / dimethylsulfoxide / 8 h / -20 °C 2: dimethylformamide / 8 h / Heating View Scheme
参考文献
Hu, Mougang; Brasseur, Nicole; Zeki Yildiz; Van Lier, Johan E.; Leznoff, Clifford C.
Journal of Medicinal Chemistry, 1998 , vol. 41, # 11 p. 1789 - 1802
