1.1: aluminum chloride / CH2Cl2 / 22 - 28 °C 1.2: aq. HCl / CH2Cl2 / -5 - 1 °C 2.1: Red-Al; sodium bis(2-methoxyethoxy)aluminum hydride / toluene; tetrahydrofuran / -10 - 0 °C 3.1: pyridine / CH2Cl2 / -5 - 0 °C 4.1: nitric acid; trifluoroacetic acid; trifluoroacetic anhydride / CH2Cl2 / -35 - -30 °C 5.1: NaOH; methanol / 23 °C 6.1: acetic acid; perchloric acid; hydrogen / Pd/C / 15.5 h / 2172.08 - 2585.81 Torr 6.2: NaHCO3 / H2O; CH2Cl2 / 23 °C / pH 8.0 View Scheme

1: With N-(diphenylmethylene)amine; tris-(dibenzylideneacetone)dipalladium(0); sodium methylate; 2,2'-bis-(diphenylphosphino)-1,1'- binaphthyl in toluene 2: With hydrogenchloride in water 3: With sodium hydroxide