5-乙酰基-6-甲基-4-苯基-3,4-二氢-1H-嘧啶-2-酮合成路线 （共 13 条）
反应条件
1-n-butyl-3-methylimidazolium tetrafluoroborate T=100°C; Biginelli condensation; 0.5 h;
参考文献
Ramos, Luciana M.; Guido, Bruna C.; Nobrega, Catharine C.; Correa, Jose R.; Silva, Rafael G.; De Oliveira, Heibbe C. B.; Gomes, Alexandre F.; Gozzo, Fabio C.; Neto, Brenno A. D.
Chemistry - A European Journal, 2013 , vol. 19, # 13 p. 4156 - 4168
反应条件
{[CuCl-(S)-3-hydroxy-2-(pyridin-4-ylmethylamino)propanoate]2*H2O}n in dichloromethane T=40°C; Biginelli pyrimidine synthesis; 12 h; Inert atmosphere;
参考文献
Wang, Miao; Xie, Ming-Hua; Wu, Chuan-De; Wang, Yan-Guang
Chemical Communications, 2009 , # 17 p. 2396 - 2398
反应条件
thiamine hydrochloride in water T=20°C; Biginelli pyrimidine synthesis; 0.25 h; Sonication;
参考文献
Mandhane, Priyanka G.; Joshi, Ratnadeep S.; Nagargoje, Deepak R.; Gill, Charansingh H.
Tetrahedron Letters, 2010 , vol. 51, # 23 p. 3138 - 3140
反应条件
1: benzyl bromide With Bi(NO3)3; tetrabutyl ammonium fluoride T=80°C; 2: urea; acetylacetone T=80°C; Biginelli reaction;
参考文献
Khodaei, Mohammad Mehdi; Khosropour, Ahmad Reza; Jowkar, Mahbubeh
Synthesis, 2005 , # 8 art. no. Z21704SS, p. 1301 - 1304
反应条件
1: benzyl chloride With Bi(NO3)3; tetrabutyl ammonium fluoride T=80°C; 2: urea; acetylacetone T=80°C; Biginelli reaction;
参考文献
Khodaei, Mohammad Mehdi; Khosropour, Ahmad Reza; Jowkar, Mahbubeh
Synthesis, 2005 , # 8 art. no. Z21704SS, p. 1301 - 1304
参考文献
Salehi, Peyman; Dabiri, Minoo; Zolfigol, Mohammad Ali; Baghbanzadeh, Mostafa
Heterocycles, 2005 , vol. 65, # 5 p. 1177 - 1181
反应条件
1: benzyl alcohol With Bi(NO3)3 in acetonitrile Heating; 2: urea; acetylacetone in acetonitrile Heating;
参考文献
Khosropour, Ahmad R.; Khodaei, Mohammd M.; Beygzadch, Mojtaba; Jokar, Mahbubeh
Heterocycles, 2005 , vol. 65, # 4 p. 767 - 773
反应条件
Bi(NO3)3 T=100°C; Biginelli reaction; 0.333333 h;
参考文献
Khosropour, Ahmad R.; Khodaei, Mohammad M.; Beygzadeh, Mojtaba
Heteroatom Chemistry, 2007 , vol. 18, # 6 p. 684 - 687
反应条件
Bi(NO3)3 T=100°C; Biginelli reaction; 0.333333 h;
参考文献
Khosropour, Ahmad R.; Khodaei, Mohammad M.; Beygzadeh, Mojtaba
Heteroatom Chemistry, 2007 , vol. 18, # 6 p. 684 - 687
反应条件
acetic acid T=150°C;
参考文献
Bakibaev, A. A.; Akhmedzhanov, R. R.; Yagovkin, A. Yu.; Novozheeva, T. P.; Filimonov, V. D.; Saratikov, A. S.
Pharmaceutical Chemistry Journal, 1993 , vol. 27, # 6 p. 401 - 406
Khimiko-Farmatsevticheskii Zhurnal, 1993 , vol. 27, # 6 p. 29 - 33
