N-苯甲酰-L-苯基丙氨酸合成路线 (共 71 条)
反应条件
α-chymotrypsin in chloroform; water also in water only; correlation with pH; Equilibrium constant;
参考文献
Doklady Chemistry, , vol. 253, p. 343 - 345
Dokl. Akad. Nauk SSSR Ser. Khim., , vol. 253, # 2 p. 358 - 361
反应条件
α-chymotrypsin chemically modified with monomethoxypolyethylene glycol (α-CT-PEG) enzymatic hydrolysis at pH 8.0 (phosphate buffer), Km value; Rate constant;
参考文献
Tetrahedron, , vol. 51, # 6 p. 1827 - 1844
反应条件
1: DCC, DMAP 2: 93 percent / Bu3SnH, AIBN / benzene / 1 h / Heating View Scheme
参考文献
Synlett, , vol. 1997, # 8 p. 950 - 952
反应条件
1.1: Ac2O / 1 h / 95 °C 2.1: 121 g / pyridine / H2O / 12 h / 20 °C 3.1: aq. NaOH / dioxane / 1 h / 20 °C 3.2: cinchonidine / ethanol / 6 h 3.3: 73.8 percent / aq. HCl / 0.5 h 4.1: 86.2 percent / pyridine / 72 h / 5 °C 5.1: 74.9 percent / NaI; Zn / dimethylformamide / 10 h / 120 °C 6.1: 82.1 percent / HCl / 10 h / Heating View Scheme
参考文献
Shiraiwa, Tadashi; Suzuki, Masahiro; Sakai, Yoshio; Nagasawa, Hisashi; Takatani, Kazuhiro; Noshi, Daisuke; Yamanashi, Kenji
Chemical and pharmaceutical bulletin, 2002 , vol. 50, # 10 p. 1362 - 1366
反应条件
tri-cyclo-hexyl-phosphine; [RhCl(η2:η2-cycloocta-1,5-diene)]2 in acetonitrile T=60°C; Racemization; 48 h;
参考文献
Hateley, Martin J.; Schichl, Daniel A.; Kreuzfeld, Hans-Joern; Beller, Matthias
Tetrahedron Letters, 2000 , vol. 41, # 20 p. 3821 - 3824
反应条件
anschliessendes Erhitzen mit <2>Naphthol;
参考文献
Ravin et al.
Journal of Biological Chemistry, 1954 , vol. 208, p. 1,2
反应条件
4-(N,N-dimethlyamino)pyridine; acetic acid; triethylamine T=60°C; 1.) 30 min; 2.) 30 min;
参考文献
Burley; Hewson
Synthesis, 1995 , # 9 p. 1151 - 1154
参考文献
Aronova,N.I. et al.
Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1968 , p. 2432 - 2435
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1968 , p. 2571 - 2575
反应条件
T=100°C; Rate constant;
参考文献
Searles; Cvejanovich
Journal of the American Chemical Society, 1950 , vol. 72, p. 3200,3201
反应条件
D-amidase-substance from pseudomonas-cultures T=37°C;
参考文献
Kameda et al.
Nature (London, United Kingdom), 1958 , vol. 181, p. 1225