N-苯甲酰-L-苯基丙氨酸合成路线 （共 71 条）
反应条件
1: acetic anhydride / 2 h / 65 °C 2: Candida antarctica B lipase; water / acetonitrile / 72 h / 37 °C / Enzymatic reaction View Scheme
参考文献
Yu, Jeong Jae; Ryoo, Jae Jeong
Bulletin of the Korean Chemical Society, 2013 , vol. 34, # 11 p. 3474 - 3476
参考文献
Ngamsom; Hickey; Greenway; Littlechild; Watts; Wiles
Journal of Molecular Catalysis B: Enzymatic, 2010 , vol. 63, # 1-2 p. 81 - 86
反应条件
polymer-supported Thermococcus litoralis L-aminoacylase T=20°C; pH=8; aq. bufferEnzymatic reaction;
参考文献
Kameda et al.
Yakugaku Zasshi, 1958 , vol. 78, p. 767
Chem.Abstr., 1958 , p. 18237
Full Text Show Details
Kameda et al.
Chemical and Pharmaceutical Bulletin, 1959 , vol. 7, p. 702,706
Yakugaku Zasshi, 1958 , vol. 78, p. 763
Chem.Abstr., 1958 , p. 18237
反应条件
D-glucose; corn steep liquor; fungus Beauveria bassiana ATCC 7159 in ethanol; water Hydrolysis; 72 h; Enzymatic reaction; Title compound not separated from byproducts;
参考文献
Holland, Herbert L.; Andreana, Peter R.; Salehzadeh-Asl, Reza; Van Vliet, Aaron; Ihasz, Nancy J.; Brown, Frances M.
Monatshefte fur Chemie, 2000 , vol. 131, # 6 p. 667 - 672
反应条件
1: acetic anhydride / 100 °C
2: oxygen / 10 percent Pd/C / acetic anhydride; acetic acid / 25 °C
View Scheme
参考文献
Bates, Robert B.; Fletcher, Frederick A.; Janda, Kim D.; Miller, William A.
Journal of Organic Chemistry, 1984 , vol. 49, # 16 p. 3038
反应条件
1: 63 percent / DCC, HOBt
2: 68 percent / NaIO4, RuCl3*3H2O / acetonitrile; CCl4 / 1.5 h / Ambient temperature; pH 3
View Scheme
参考文献
Ranganathan; Vaish; Shah
Journal of the American Chemical Society, 1994 , vol. 116, # 15 p. 6545 - 6557
反应条件
1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 1 h / 0 °C
2: tetrabutylammomium bromide; potassium carbonate / dichloromethane / 48 h / -20 °C
View Scheme
参考文献
Tari, Silvia; Avila, Angel; Chinchilla, Rafael; Najera, Carmen
Tetrahedron Asymmetry, 2012 , vol. 23, # 2 p. 176 - 180
反应条件
1: Ac2O / 1 h / 95 °C
2: 121 g / pyridine / H2O / 12 h / 20 °C
View Scheme
参考文献
Shiraiwa, Tadashi; Suzuki, Masahiro; Sakai, Yoshio; Nagasawa, Hisashi; Takatani, Kazuhiro; Noshi, Daisuke; Yamanashi, Kenji
Chemical and pharmaceutical bulletin, 2002 , vol. 50, # 10 p. 1362 - 1366
反应条件
1: Ac2O / 1 h / 95 °C
2: 121 g / pyridine / H2O / 12 h / 20 °C
3: 89.2 percent / aq. NaOH / dioxane / 1 h / 20 °C
View Scheme
参考文献
Shiraiwa, Tadashi; Suzuki, Masahiro; Sakai, Yoshio; Nagasawa, Hisashi; Takatani, Kazuhiro; Noshi, Daisuke; Yamanashi, Kenji
Chemical and pharmaceutical bulletin, 2002 , vol. 50, # 10 p. 1362 - 1366
反应条件
rat cecal content
T=37°C; pH=6.8; aq. phosphate buffer;
参考文献
Kong, Hyesik; Kim, Hyunjeong; Do, Heejeong; Lee, Yonghyun; Hong, Sungchae; Yoon, Jeong-Hyun; Jung, Yunjin; Kim, Young Mi
Biopharmaceutics and Drug Disposition, 2011 , vol. 32, # 6 p. 343 - 354
