1-(3-硝基苯基)-1H-吡唑合成路线 （共 9 条）
反应条件
caesium carbonate; copper(I) bromide in dimethyl sulfoxide T=80°C; Ullmann coupling; 24 h;
参考文献
Yang, Minghua; Liu, Fei
Journal of Organic Chemistry, 2007 , vol. 72, # 23 p. 8969 - 8971
反应条件
caesium carbonate in 1-methyl-pyrrolidin-2-one T=100°C; 17 h;
参考文献
BRISTOL-MYERS SQUIBB COMPANY
Patent: WO2003/90912 A1, 2003 ;
Location in patent: Page/Page column 85-86 ;
WO 03/090912 A1
反应条件
caesium carbonate; copper(I) oxide in N,N-dimethyl-formamide T=110°C; 18 h;
参考文献
Correa, Arkaitz; Bolm, Carsten
Advanced Synthesis and Catalysis, 2007 , vol. 349, # 17-18 p. 2673 - 2676
反应条件
in ethanol 1 h; Heating;
参考文献
De La Hoz, Antonio; Diaz-Ortiz, Angel; Elguero, Jose; Martinez, Luis J.; Moreno, Andres; Sanchez-Migallon, Ana
Tetrahedron, 2001 , vol. 57, # 20 p. 4397 - 4403
参考文献
Finar; Hurlock
Journal of the Chemical Society, 1957 , p. 3024,3025
参考文献
Finar; Godfrey
Journal of the Chemical Society, 1954 , p. 2293,2295
反应条件
1.1: 68 percent / hydrazine hydrate / Pd/C / ethanol / 1 h / Heating 2.1: NaNO2; HCl / H2O / 0 - 5 °C 2.2: 64 percent / CuCN / H2O / 0.33 h / 60 °C View Scheme
参考文献
De La Hoz, Antonio; Diaz-Ortiz, Angel; Elguero, Jose; Martinez, Luis J.; Moreno, Andres; Sanchez-Migallon, Ana
Tetrahedron, 2001 , vol. 57, # 20 p. 4397 - 4403
反应条件
hydrogen; palladium 10 on activated carbon in ethyl acetate T=20°C; 17 h;
参考文献
BRISTOL-MYERS SQUIBB COMPANY
Patent: WO2003/90912 A1, 2003 ;
Location in patent: Page/Page column 86 ;
WO 03/090912 A1
反应条件
sulfuric acid; nitric acid
参考文献
Finar; Hurlock
Journal of the Chemical Society, 1957 , p. 3024,3025
