(2R)-氨基(3-氯苯基)乙酸合成路线 (共 6 条)
反应条件
potassium phosphate buffer; Rhodococcus sp. AJ270 cells in water T=30°C; pH=7.62; 2.7 h;
参考文献
Wang, Mei-Xiang; Lin, Shuang-Jun
Journal of Organic Chemistry, 2002 , vol. 67, # 18 p. 6542 - 6545
反应条件
Rhodococcus sp. AJ270 in phosphate buffer T=30°C; pH=7.62; 3 h; Title compound not separated from byproducts;
参考文献
Wang, Mei-Xiang; Lin, Shuang-Jun
Tetrahedron Letters, 2001 , vol. 42, # 39 p. 6925 - 6927
反应条件
1: NH4ClNH4Cl 2: Rhodococcus sp. AJ270 / aq. phosphate buffer / 3 h / 30 °C / pH 7.62 View Scheme
参考文献
Garcia, Maria J.; Azerad, Robert
Tetrahedron Asymmetry, 1997 , vol. 8, # 1 p. 85 - 92
反应条件
1: 76 percent / 0.1 M Tris-HCl buffer / 21 h / 50 °C / Agrobacterium tumefaciens 2: 68 percent / NaNO2, 3.5 N aq. HCl / 60 h / Ambient temperature View Scheme
参考文献
Garcia, Maria J.; Azerad, Robert
Tetrahedron Asymmetry, 1997 , vol. 8, # 1 p. 85 - 92
反应条件
potassium hydroxide; ammonia; (+)-(1S,2R)-N-hexadecyl-N-methylephedrinium bromide; lithium chloride in ethanol 5 deg C, 4 h, RT, overnight; asymmetric induction; Product distribution;
参考文献
Zhang, Yongmin; Li, Weixing
Synthetic Communications, 1988 , vol. 18, # 14 p. 1685 - 1690
反应条件
sodium dihydrogenphosphate; superheavy water T=80.2 - 110.3°C; pH 10.0; Ea, ΔH(excit.), ΔS(excit.); Thermodynamic dataRate constant;
参考文献
Smith, Grant Gill; Sivakua, Thipamon
Journal of Organic Chemistry, 1983 , vol. 48, # 5 p. 627 - 634