2,4,6-三甲氧基苯甲腈合成路线 （共 23 条）
反应条件
1-methyl-pyrrolidin-2-one; hydroxylamine hydrochloride T=100°C; Condensation; 0.25 h; microwave irradiation;
参考文献
Chakraborti, Asit K.; Kaur, Gurmeet
Tetrahedron, 1999 , vol. 55, # 46 p. 13265 - 13268
反应条件
1: With trichlorophosphate T=40°C; Vilsmeier-Haack reaction; 3 h; 2: With 1,3-Diiodo-5,5-dimethyl-2,4-imidazolidinedione; ammonia in water T=20°C; 3 h; regioselective reaction;
参考文献
Ushijima, Sousuke; Moriyama, Katsuhiko; Togo, Hideo
Tetrahedron, 2012 , vol. 68, # 24 p. 4588 - 4595
反应条件
1: With magnesium in tetrahydrofuran T=20°C; 2: With ammonia; iodine in tetrahydrofuran; water T=20°C;
参考文献
Ishii, Genki; Moriyama, Katsuhiko; Togo, Hideo
Tetrahedron Letters, 2011 , vol. 52, # 18 p. 2404 - 2406
反应条件
1: With magnesium in tetrahydrofuran T=20°C; 2 h; 2: With N,N-dimethyl-formamide in tetrahydrofuran T=0°C; 2 h; 3: With ammonia; iodine in tetrahydrofuran; water T=20°C; 2 h;
参考文献
Ishii, Genki; Harigae, Ryo; Moriyama, Katsuhiko; Togo, Hideo
Tetrahedron, 2013 , vol. 69, # 5 p. 1462 - 1469
反应条件
CuF2; 1,10-phenanthroline; oxygen; lithium carbonate in dimethyl sulfoxide T=150°C; 36 h; Sealed tube;
参考文献
Zheng, Kui; Liu, Bin; Chen, Shuyou; Chen, Fan
Tetrahedron Letters, 2013 , vol. 54, # 38 p. 5250 - 5252
反应条件
sodium azide; CuSO4‵5H2O; [bis(acetoxy)iodo]benzene in acetonitrile T=-40 - 25°C; Inert atmosphere;
参考文献
Zhou, Wang; Zhang, Liangren; Jiao, Ning
Angewandte Chemie, International Edition, 2009 , vol. 48, # 38 p. 7094 - 7097
Angewandte Chemie, 2009 , vol. 121, # 38 p. 7228 - 7231
反应条件
sulfuric acid; silica gel 0.0333333 h; Irradiation;
参考文献
Kumar, H.M. Sampath; Mohanty, Pradyumna K.; Kumar, M. Suresh; Yadav
Synthetic Communications, 1997 , vol. 27, # 8 p. 1327 - 1333
反应条件
copper(I) oxide in N,N-dimethyl-formamide T=130°C; 12 h;
参考文献
Wen, Qiaodong; Jin, Jisong; Mei, Yuncai; Lu, Ping; Wang, Yanguang
European Journal of Organic Chemistry, 2013 , # 19 p. 4032 - 4036
反应条件
oxygen; copper diacetate; palladium diacetate in dimethyl sulfoxide T=130°C;
参考文献
Yan, Guobing; Kuang, Chunxiang; Zhang, Yan; Wang, Jianbo
Organic Letters, 2010 , vol. 12, # 5 p. 1052 - 1055
反应条件
N,N,N',N,-tetramethylethylenediamine; copper diacetate; ammonium hydrogen carbonate T=150°C; 22 h; sealed tube;
参考文献
Zhang, Guoying; Ren, Xinyi; Chen, Jianbin; Hu, Maolin; Cheng, Jiang
Organic Letters, 2011 , vol. 13, # 19 p. 5004 - 5007
