2,3-二氨基-5-氯吡啶合成路线 （共 15 条）
反应条件
hydrogen; nickel in methanol P=1034.3 - 2068.6 Torr; 3 h;
参考文献
Cai, Sui Xiong; Huang, Jin-Cheng; Espitia, Stephen A.; Tran, Minhtam; Ilyin, Victor I.; Hawkinson, Jon E.; Woodward, Richard M.; Weber, Eckard; Keana, John F.W.
Journal of Medicinal Chemistry, 1997 , vol. 40, # 22 p. 3679 - 3686
反应条件
1: 56 percent / 97percent H2SO4, 70percent HNO3 / 1 h / 55 - 60 °C 2: 96 percent / H2 / Raney Ni / methanol / 3 h / 1034.3 - 2068.6 Torr View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 40, # 22 p. 3679 - 3686
参考文献
State of Oregon, acting by and through The Oregon State Board of Higher Education, acting for and on behalf of The Oregon Health Sciences University and The University of Oregon, Eugene Oregon; The Regents of the University of California; ACEA Pharmaceuticals, Inc.
Patent: US5620978 A1, 1997 ;
US 5620978 A
参考文献
Chemische Berichte, , vol. 60, p. 775
Zhurnal Russkago Fiziko-Khimicheskago Obshchestva, , vol. 59, p. 417
参考文献
Vaughan et al.
Journal of the American Chemical Society, 1949 , vol. 71, p. 1885
参考文献
Vaughan et al.
Journal of the American Chemical Society, 1949 , vol. 71, p. 1885
反应条件
in pyridine 5 h; Heating;
参考文献
Yutilov, Yu.M.; Svertilova, I.A.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1988 , p. 653 - 658
Khimiya Geterotsiklicheskikh Soedinenii, 1988 , vol. 24, # 6 p. 799 - 804
参考文献
Vaughan et al.
Journal of the American Chemical Society, 1949 , vol. 71, p. 1885
反应条件
2: palladium; H2O / Hydrogenation View Scheme
参考文献
Vaughan et al.
Journal of the American Chemical Society, 1949 , vol. 71, p. 1885
反应条件
2: palladium/CaCO3 / Hydrogenation View Scheme
参考文献
Vaughan et al.
Journal of the American Chemical Society, 1949 , vol. 71, p. 1885
