2,4,6-三(三氟甲基)苯胺合成路线 （共 6 条）
反应条件
copper(I) oxide; sodium azide in dimethyl sulfoxide T=80°C; 1 h; Inert atmosphere;
参考文献
Edelbach, Brian L.; Pharoah, Blaze M.; Bellows, Sarina M.; Thayer, Peter R.; Fennie, Charles N.; Cowley, Ryan E.; Holland, Patrick L.
Synthesis (Germany), 2012 , vol. 44, # 23 art. no. SS-2012-M0747-OP, p. 3595 - 3597
反应条件
potassium hydroxide; bromine T=0°C; 12 h;
参考文献
Ahlemann, Jens-T; Roesky, Herbert W.; Noltemeyer, Mathias; Schmidt, Hans-G.; Markovsky, Leonid N.; Shermolovich, Yuri G.
Journal of Fluorine Chemistry, 1998 , vol. 87, # 1 p. 87 - 90
反应条件
1: 75 percent / n-BuLi / hexane; diethyl ether / 1.) -5 deg C, 2.) 2 h 2: 85 percent / PCl5 / CCl4 / 1 h / Heating 3: 90 percent / NH3 / acetone / 12 h / Heating 4: 75 percent / Br2, aq. KOH / 12 h / 0 °C View Scheme
参考文献
Journal of Fluorine Chemistry, , vol. 87, # 1 p. 87 - 90
反应条件
1: 85 percent / PCl5 / CCl4 / 1 h / Heating 2: 90 percent / NH3 / acetone / 12 h / Heating 3: 75 percent / Br2, aq. KOH / 12 h / 0 °C View Scheme
参考文献
Journal of Fluorine Chemistry, , vol. 87, # 1 p. 87 - 90
反应条件
1: 90 percent / NH3 / acetone / 12 h / Heating 2: 75 percent / Br2, aq. KOH / 12 h / 0 °C View Scheme
参考文献
Journal of Fluorine Chemistry, , vol. 87, # 1 p. 87 - 90
反应条件
sulfuric acid; dihydrogen peroxide; iron(II) sulfate in water; dimethyl sulfoxide
参考文献
Journal of Fluorine Chemistry, , vol. 131, # 1 p. 98 - 105
