2-氯-3,5-二硝基吡啶合成路线 （共 24 条）
反应条件
PSHF in acetonitrile T=20°C; 48 h;
参考文献
Darabantu, Mircea; Lequeux, Thierry; Pommelet, Jean-Claude; Ple, Nelly; Turck, Alain
Tetrahedron, 2001 , vol. 57, # 4 p. 739 - 750
反应条件
1: 89 percent / aq. NH4OH / ethanol / 0.25 h / Ambient temperature 2: 80 percent / aq.(NH4)2S / methanol / 0.5 h / Heating View Scheme
参考文献
Cai, Sui Xiong; Huang, Jin-Cheng; Espitia, Stephen A.; Tran, Minhtam; Ilyin, Victor I.; Hawkinson, Jon E.; Woodward, Richard M.; Weber, Eckard; Keana, John F.W.
Journal of Medicinal Chemistry, 1997 , vol. 40, # 22 p. 3679 - 3686
反应条件
1: 89 percent / aq. NH4OH / ethanol / 0.25 h / Ambient temperature 2: 80 percent / aq.(NH4)2S / methanol / 0.5 h / Heating 3: 74 percent / aq.HCl / 16 h / Heating View Scheme
参考文献
Cai, Sui Xiong; Huang, Jin-Cheng; Espitia, Stephen A.; Tran, Minhtam; Ilyin, Victor I.; Hawkinson, Jon E.; Woodward, Richard M.; Weber, Eckard; Keana, John F.W.
Journal of Medicinal Chemistry, 1997 , vol. 40, # 22 p. 3679 - 3686
反应条件
in chloroform 0.25 h;
参考文献
European Journal of Medicinal Chemistry, , vol. 27, # 4 p. 359 - 368
反应条件
water T=25°C; Rate constant;
参考文献
Brenelli, Eugenia Cristina Souza; Moran, Paulo Jose Samenho
Journal of Chemical Research, Miniprint, 1989 , # 12 p. 2816 - 2825
反应条件
1: sodium acetate / ethanol / 4 h / Heating
2: pyridine / 3 h / Heating
View Scheme
参考文献
Kumar, Neeraj; Singh, Girwar; Khatoon, Shabana; Yadav, Ashok K.
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2003 , vol. 42, # 8 p. 2015 - 2018
参考文献
Asghar, Basim H.
E-Journal of Chemistry, 2010 , vol. 7, # 1 p. 253 - 259
反应条件
in methanol
T=20°C; Substitution;
参考文献
El Hegazy, Fatma El-Zahraa M.; Abdel Fattah, Soheir Z.; Hamed, Ezzat A.; Sharaf, Saber M.
Journal of Physical Organic Chemistry, 2000 , vol. 13, # 9 p. 549 - 554
反应条件
1: ethanol
2: 1,4-diaza-bicyclo[2.2.2]octane / dimethyl sulfoxide / 25 °C
View Scheme
参考文献
Asghar, Basim H.
Monatshefte fur Chemie, 2013 , vol. 144, # 3 p. 301 - 306
反应条件
1: 1.) Na / 1.) 120 deg C, 30 min, 2.) toluene, reflux, 8 h
2: 50percent aq. H2SO4 / 8 h / 120 - 124 °C
View Scheme
参考文献
Liu, Mao-Chin; Lin, Tai-Shun; Sartorelli, Alan C.
Synthetic Communications, 1990 , vol. 20, # 19 p. 2965 - 2970
