反应条件
1: 1.) tetramethylethylenediamine (TMEDA), BuLi / 1.) petroleum ether, hexane, RT, 0.5 h, 2.) petroleum ether, hexane, RT, 0.5 h
2: 1.) Br2, 2.) diisopropylamine, BuLi
3: LiAlH4 / tetrahydrofuran / 1.5 h / Heating
View Scheme
参考文献
Jacob, Peyton; Shulgin, Alexander T.
Journal of Medicinal Chemistry, 1984 , vol. 27, # 7 p. 881 - 888