5-硝基苯并[b]噻吩-2-羧酸乙酯合成路线 （共 17 条）
反应条件
potassium carbonate in N,N-dimethyl-formamide T=60°C; 4 h;
参考文献
Cai, Jin; Zhang, Shaoning; Zheng, Ming; Wu, Xiaoqing; Chen, Junqing; Ji, Min
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 2 p. 806 - 810
反应条件
hydrogenchloride; potassium carbonate in methanol; N,N-dimethyl-formamide
参考文献
Kori, Masakuni; Miki, Takashi; Nishimoto, Tomoyuki; Tozawa, Ryuichi
Patent: US2003/78251 A1, 2003 ;
反应条件
in DMF (N,N-dimethyl-formamide); mineral oil T=100°C; 6 h;
参考文献
QUEEN MARY and WESTFIELD COLLEGE; UNIVERSITY COLLEGE LONDON; BARTS AND THE LONDON NHS TRUST
Patent: WO2004/46094 A1, 2004 ;
Location in patent: Page 60 ;
反应条件
triethylamine in ethanol
参考文献
Vita-Invest, SA
Patent: US6262056 B1, 2001 ;
反应条件
1: With sodium sulfide in ethanol 2 h; Heating; 2: ethyl bromoacetate in ethanol T=50°C; 3: 2-chloro-5-nitro-benzaldehyde With triethylamine in ethanol T=20°C;
参考文献
Perez-Silanes; Martinez-Esparza; Oficialdegui; Villanueva; Orus; Monge
Journal of Heterocyclic Chemistry, 2001 , vol. 38, # 5 p. 1025 - 1030
参考文献
Justus Liebigs Annalen der Chemie, , vol. 527, p. 83,101
反应条件
1: Na2S; Na2CO3; aqueous ethanol / Erhitzen der Reaktionsloesung mit wss.Natrium-chloracetat-Loesung 2: aq. NaOH solution View Scheme
参考文献
Justus Liebigs Annalen der Chemie, , vol. 527, p. 83,101
反应条件
1: aq. NaOH solution View Scheme
参考文献
Justus Liebigs Annalen der Chemie, , vol. 527, p. 83,101
反应条件
1: ethanol; sodium disulfide / anschliessend Erwaermen mit Natriumsulfid und wss. Natronlauge und Erwaermen des Reaktionsgemisches mit Natrium-chloracetat in Wasser View Scheme
参考文献
Justus Liebigs Annalen der Chemie, , vol. 527, p. 83,101
参考文献
Justus Liebigs Annalen der Chemie, , vol. 527, p. 83,101
