反应条件
1.1: sodium ethanolate / toluene / 0.5 h / 21 - 24 °C / |Inert atmosphere; |Large scale
1.2: 2.5 h / 20 - 25 °C / |Large scale
2.1: diisobutylaluminium hydride / toluene / 2 h / 15 - 20 °C / |Inert atmosphere; |Large scale
3.1: methanesulfonyl chloride; N,N-dimethyl-formamide / 1.5 h / 70 °C / |Cooling with ice
View Scheme
参考文献
Deussen, Heinz-Josef; Jeppesen, Lone; Schaerer, Norbert; Junager, Finn; Bentzen, Bjorn; Weber, Beat; Weil, Volker; Mozer, Sandor Josef; Sauerberg, Per
Organic Process Research and Development, 2004 , vol. 8, # 3 p. 363 - 371
