6-叔丁氧羰基氨基吡啶-2-羧酸合成路线 (共 4 条)
反应条件
sodium hydroxide; diphenylphosphoranyl azide; triethylamine; ethyl acetate in tert-butyl alcohol
参考文献
US6025352 A1, ;
US6030965 A1, ;
反应条件
TEA; diphenyl phosphoryl azide Curtius rearrangement;
参考文献
Cho, Aesop; Glinka, Tomasz W.; Ludwikow, Maria; Fan, Andrew T.; Wang, Michael; Hecker, Scott J.
Bioorganic and Medicinal Chemistry Letters, 2001 , vol. 11, # 2 p. 137 - 140
反应条件
sulfuric acid 5 h; Inert atmosphereReflux;
参考文献
Frimannsson, Daniel O.; McCabe, Thomas; Schmitt, Wolfgang; Lawler, Mark; Gunnlaugsson, Thorfinnur
Supramolecular Chemistry, 2010 , vol. 22, # 9 p. 483 - 490
反应条件
1: POCl3 / dimethylformamide; ethyl acetate View Scheme
参考文献
Essential Therapeutics, Inc.
Patent: US6723716 B1, 2004 ;