1-(4-甲基苯基)-3-苯基-1,3-丙烷二酮合成路线 （共 37 条）
反应条件
1: cyanoacetic acid amide; ethanol; diethylamine 2: aqueous sulfuric acid View Scheme
参考文献
Basu
Journal of the Indian Chemical Society, 1930 , vol. 7, p. 815,823
反应条件
anhydrous iron chloride; tert.-butylnitrite T=30°C; 12 h; Under airNeat (no solvent);
参考文献
Huang, Lehao; Cheng, Kai; Yao, Bangben; Xie, Yongju; Zhang, Yuhong
Journal of Organic Chemistry, 2011 , vol. 76, # 14 p. 5732 - 5737
反应条件
[NEt3Me]I; water; dihydrogen peroxide in acetonitrile T=20°C; 15 h;
参考文献
Yuan, Yu; Ji, Xiang; Zhao, Dongbo
European Journal of Organic Chemistry, 2010 , # 27 p. 5274 - 5278
反应条件
sodium methylate in anhydrous xylene
Claisen Condensation; 1.25 h; Inert atmosphereRefluxMicrowave irradiation;
参考文献
DEXERA; Honnart, Stephane; Galy-Jammou, Philippe
Patent: US2014/88325 A1, 2014 ;
Location in patent: Paragraph 0159; 0160; 0161; 0162; 0163 ;
反应条件
sodium methylate in anhydrous xylene
参考文献
Witco Corporation
Patent: US5015777 A1, 1991 ;
反应条件
lithium perchlorate; triethylamine in acetonitrile
0.333333 h; Irradiation;
参考文献
Hasegawa, Eietsu; Ishiyama, Kenyuki; Horaguchi, Takaaki; Shimizu, Takahachi
Journal of Organic Chemistry, 1991 , vol. 56, # 4 p. 1631 - 1635
反应条件
samarium diiodide in tetrahydrofuran
T=20°C; Reformatsky type reaction; 1 h;
参考文献
Baek, Heung Soo; Yoo, Byung Woo; Keum, Sam Rok; Yoon, Cheol Min; Kim, Sung Hoon; Kim, Joong Hyup
Synthetic Communications, 2000 , vol. 30, # 1 p. 31 - 38
反应条件
sodium hydride in tetrahydrofuran
0.5 h; Heating;
参考文献
Hasegawa, Eietsu; Ishiyama, Kenyuki; Horaguchi, Takaaki; Shimizu, Takahachi
Journal of Organic Chemistry, 1991 , vol. 56, # 4 p. 1631 - 1635
反应条件
1: acetophenone With lithium hexamethyldisilazane in tetrahydrofuran; toluene
T=0°C;
2: 4-methyl-benzoyl chloride in tetrahydrofuran; toluene
0.0166667 h;
参考文献
Heller, Stephen T.; Natarajan, Swaminathan R.
Organic Letters, 2006 , vol. 8, # 13 p. 2675 - 2678
反应条件
mercury dichloride; mercury(II) oxide in methanol; water
2 h; Heating;
参考文献
Stahl, Ingfried
Chemische Berichte, 1985 , vol. 118, # 5 p. 1798 - 1808
