5-甲基-2-(1-甲基乙烯基)-4-己烯-1-醇乙酸酯合成路线 （共 23 条）
反应条件
pyridine; potassium diazodicarboxylate in acetic acid T=50°C; 81 h; Yield given. Yields of byproduct given;
参考文献
King, Chi-Hsin R.; Poulter, C. Dale
Journal of the American Chemical Society, 1982 , vol. 104, # 5 p. 1413 - 1420
反应条件
Porcine Pancreas Lipase; sodium phosphate buffer T=20°C; pH=7; 0.5 h; Enzymatic reaction; Title compound not separated from byproducts;
参考文献
Zada, Anat; Harel, Miriam
Tetrahedron Asymmetry, 2004 , vol. 15, # 15 p. 2339 - 2343
反应条件
potassium hydroxide in ethanol 3 h; Ambient temperature;
参考文献
Fleming, Ian; Lee, Duckhee
Journal of the Chemical Society - Perkin Transactions 1, 1998 , # 17 p. 2701 - 2709
反应条件
CuCN*2LiCl in tetrahydrofuran
T=0°C; 0.3 h;
参考文献
Yanagisawa; Nomura; Noritake; Yamamoto
Synthesis, 1991 , # 12 p. 1130 - 1136
反应条件
aluminium trichloride in ethyl acetate
0.0833333 h; Ambient temperature;
参考文献
King, Chi-Hsin R.; Poulter, C. Dale
Journal of the American Chemical Society, 1982 , vol. 104, # 5 p. 1413 - 1420
反应条件
formic acid; triethylamine; tetrakis(triphenylphosphine) palladium(0) in tetrahydrofuran
T=20°C; 7 h; Title compound not separated from byproducts;
参考文献
Araki, Shuki; Kambe, Shinya; Kameda, Keiko; Hirashita, Tsunehisa
Synthesis, 2003 , # 5 p. 751 - 754
反应条件
1: 79 percent / N,N'-dimethylimidazolidinone; H2O; InI / Pd(Ph3P)4 / 48 h / 20 °C
2: 77 percent / DMAP / CH2Cl2 / 24 h / 20 °C
3: BuZnCl / Pd(Ph3P)4 / tetrahydrofuran / 2 h / Heating
View Scheme
参考文献
Araki, Shuki; Kambe, Shinya; Kameda, Keiko; Hirashita, Tsunehisa
Synthesis, 2003 , # 5 p. 751 - 754
反应条件
1: 10 percent / N,N'-dimethylimidazolidinone; H2O; InI / Pd(Ph3P)4 / 48 h / 20 °C
2: 87 percent / N,N'-dimethylimidazolidinone; aq. HCl / 2 h / 20 °C
3: 77 percent / DMAP / CH2Cl2 / 24 h / 20 °C
4: BuZnCl / Pd(Ph3P)4 / tetrahydrofuran / 2 h / Heating
View Scheme
参考文献
Araki, Shuki; Kambe, Shinya; Kameda, Keiko; Hirashita, Tsunehisa
Synthesis, 2003 , # 5 p. 751 - 754
反应条件
1: 77 percent / DMAP / CH2Cl2 / 24 h / 20 °C
2: BuZnCl / Pd(Ph3P)4 / tetrahydrofuran / 2 h / Heating
View Scheme
参考文献
Araki, Shuki; Kambe, Shinya; Kameda, Keiko; Hirashita, Tsunehisa
Synthesis, 2003 , # 5 p. 751 - 754
反应条件
1: 87 percent / N,N'-dimethylimidazolidinone; aq. HCl / 2 h / 20 °C
2: 77 percent / DMAP / CH2Cl2 / 24 h / 20 °C
3: BuZnCl / Pd(Ph3P)4 / tetrahydrofuran / 2 h / Heating
View Scheme
参考文献
Araki, Shuki; Kambe, Shinya; Kameda, Keiko; Hirashita, Tsunehisa
Synthesis, 2003 , # 5 p. 751 - 754
