反-4-(叔丁基二苯基硅氧基)-L-脯氨酸合成路线 （共 7 条）
反应条件
palladium 10 on activated carbon; hydrogen in methanol T=20°C; P=760.051 Torr; 3 h;
参考文献
Freund, Matthias H.; Tsogoeva, Svetlana B.
Synlett, 2011 , # 4 p. 503 - 507
反应条件
1: With 1,8-diazabicyclo[5.4.0]undec-7-ene in acetonitrile T=0 - 20°C; 24 h; 2: With sodium hydroxide in tetrahydrofuran; methanol; water T=20°C; 1.5 h;
参考文献
Delaney, Joshua P.; Brozinski, Hannah L.; Henderson, Luke C.
Organic and Biomolecular Chemistry, 2013 , vol. 11, # 18 p. 2951 - 2960
反应条件
1: 100 percent / imidazole / dimethylformamide / 12 h / 20 °C 2: 99 percent / H2 / Pd/C / methanol / 12 h / 20 °C / atmospheric pressure View Scheme
参考文献
Organic Letters, , vol. 7, # 19 p. 4185 - 4188
反应条件
1: 100 percent / imidazole / dimethylformamide / 12 h / 20 °C 2: 99 percent / H2 / Pd/C / methanol / 12 h / 20 °C / atmospheric pressure View Scheme
参考文献
Organic Letters, , vol. 7, # 19 p. 4185 - 4188
反应条件
1,8-diazabicyclo[5.4.0]undec-7-ene in acetonitrile T=0 - 20°C; 24 h;
参考文献
Opalka, Suzanne M.; Steinbacher, Jeremy L.; Lambiris, Brandon A.; McQuade, D. Tyler
Journal of Organic Chemistry, 2011 , vol. 76, # 16 p. 6503 - 6517
反应条件
1: sodium hydrogencarbonate / 1,4-dioxane; water / 17 h / 20 °C 2: sodium hydrogencarbonate / N,N-dimethyl-formamide / 20 h / 20 °C 3: 1H-imidazole / N,N-dimethyl-formamide / 48 h / 20 °C 4: palladium 10 on activated carbon; hydrogen / methanol / 3 h / 20 °C / 760.05 Torr View Scheme
参考文献
Synlett, , # 4 p. 503 - 507
反应条件
1: sodium hydrogencarbonate / N,N-dimethyl-formamide / 20 h / 20 °C 2: 1H-imidazole / N,N-dimethyl-formamide / 48 h / 20 °C 3: palladium 10 on activated carbon; hydrogen / methanol / 3 h / 20 °C / 760.05 Torr View Scheme
参考文献
Synlett, , # 4 p. 503 - 507
