反应条件
Stage #1: <a href="#" onclick="return RXDsubstances(event, this, '1072103', constants.ctx, '0')">ortho-methylbenzoic acid</a> <b>With</b> <a href="#" onclick="return RXDsubstances(event, this, '3587206', constants.ctx, '0')">sec.-butyllithium</a> <b>in</b> <a href="#" onclick="return RXDsubstances(event, this, '102391', constants.ctx, '0')">tetrahydrofuran</a>; <a href="#" onclick="return RXDsubstances(event, this, '1730733', constants.ctx, '0')">hexane</a>; <a href="#" onclick="return RXDsubstances(event, this, '1900225', constants.ctx, '0')">cyclohexane</a> <br />T=-90°C; 0.75 h; <br />Stage #2: <a href="#" onclick="return RXDsubstances(event, this, '471223', constants.ctx, '0')">benzaldehyde</a> <b>in</b> <a href="#" onclick="return RXDsubstances(event, this, '102391', constants.ctx, '0')">tetrahydrofuran</a>; <a href="#" onclick="return RXDsubstances(event, this, '1730733', constants.ctx, '0')">hexane</a>; <a href="#" onclick="return RXDsubstances(event, this, '1900225', constants.ctx, '0')">cyclohexane</a> <br />T=-90 - 20°C; <br />Stage #3: <b>With</b> <a href="#" onclick="return RXDsubstances(event, this, '1098214', constants.ctx, '0')">hydrogenchloride</a>; <a href="#" onclick="return RXDsubstances(event, this, '3587155', constants.ctx, '0')">water</a>; <a href="#" onclick="return RXDsubstances(event, this, '4371014', constants.ctx, '0')">ammonium chloride</a> <b>in</b> <a href="#" onclick="return RXDsubstances(event, this, '102391', constants.ctx, '0')">tetrahydrofuran</a>; <a href="#" onclick="return RXDsubstances(event, this, '1730733', constants.ctx, '0')">hexane</a>; <a href="#" onclick="return RXDsubstances(event, this, '1900225', constants.ctx, '0')">cyclohexane</a> <br />T=20°C; pH=2 - 3; 1.5 h; <br />
参考文献
Shinkaruk, Svitlana; Bennetau, Bernard; Babin, Pierre; Schmitter, Jean-Marie; Lamothe, Valerie; Bennetau-Pelissero, Catherine; Urdaci, Maria C. Bioorganic and Medicinal Chemistry, 2008 , vol. 16, # 20 p. 9383 - 9391
