(4-氧代-3,4-二氢二氮杂萘-1-基)-乙酸乙酯合成路线 （共 6 条）
反应条件
hydrazine hydrate in ethanol T=20 - 90°C; 2 h;
参考文献
Agrawal, Madhavi; Kharkar, Prashant; Moghe, Sonali; Mahajan, Tushar; Deka, Vaishali; Thakkar, Chandni; Nair, Amrutha; Mehta, Chirag; Bose, Julie; Kulkarni-Almeida, Asha; Bhedi, Dilip; Vishwakarma, Ram A.
Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 20 p. 5740 - 5743
反应条件
toluene-4-sulfonic acid; hydrazine hydrate T=20°C; 0.133333 h;
参考文献
Sriram, Dharmarajan; Yogeeswari, Perumal; Senthilkumar, Palaniappan; Sangaraju, Dewakar; Nelli, Rohit; Banerjee, Debjani; Bhat, Pritesh; Manjashetty, Thimmappa H.
Chemical Biology and Drug Design, 2010 , vol. 75, # 4 p. 381 - 391
反应条件
1: 60 percent / zinc-copper couple / tetrahydrofuran; dimethylformamide / 3 h / Heating 2: hydrazine hydrate / ethanol / Heating View Scheme
参考文献
Journal of Organic Chemistry, , vol. 56, # 7 p. 2587 - 2589
反应条件
hydrazine hydrate in ethanol Heating;
参考文献
Mylari, Banavara L.; Zembrowski, William J.
Journal of Organic Chemistry, 1991 , vol. 56, # 7 p. 2587 - 2589
反应条件
lithium hydroxide hydrate in tetrahydrofuran; methanol; water T=20°C;
参考文献
Agrawal, Madhavi; Kharkar, Prashant; Moghe, Sonali; Mahajan, Tushar; Deka, Vaishali; Thakkar, Chandni; Nair, Amrutha; Mehta, Chirag; Bose, Julie; Kulkarni-Almeida, Asha; Bhedi, Dilip; Vishwakarma, Ram A.
Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 20 p. 5740 - 5743
反应条件
1: ethyl 1,2-dihydro-1-oxophthalazin-4-ylacetate With sodium hydroxide in tetrahydrofuran
T=40 - 50°C; 0.5 h;
2: 1-bromo-4-bromomethyl-3-fluorobenzene in tetrahydrofuran
T=50 - 60°C; 2 h;
3: With acetic acid in tetrahydrofuran; water
pH=2 - 3;
参考文献
Sriram, Dharmarajan; Yogeeswari, Perumal; Senthilkumar, Palaniappan; Sangaraju, Dewakar; Nelli, Rohit; Banerjee, Debjani; Bhat, Pritesh; Manjashetty, Thimmappa H.
Chemical Biology and Drug Design, 2010 , vol. 75, # 4 p. 381 - 391
